Ecosyste.ms: Papers

10.1128/mSystems.00821-20

Struggle To Survive: the Choir of Target Alteration, Hydrolyzing Enzyme, and Plasmid Expression as a Novel Aztreonam-Avibactam Resistance Mechanism
Cited by: 20
Author(s): Ke Ma, Yu Feng, Alan McNally, Zhiyong Zong
Software Mentions: 1
Published: almost 4 years ago

10.1007/s00439-020-02150-6

Ethnogeographic and inter-individual variability of human ABC transporters
Cited by: 32
Author(s): Qingyang Xiao, Yitian Zhou, Volker M. Lauschke
Software Mentions: 1
Published: over 4 years ago

10.1007/s00439-019-02081-x

The genetic landscape of the human solute carrier (SLC) transporter superfamily
Cited by: 70
Author(s): L.C. Schaller, Volker M. Lauschke
Software Mentions: 1
Published: about 5 years ago

10.1186/1479-7364-7-10

Extrapolating the effect of deleterious nsSNPs in the binding adaptability of flavopiridol with CDK7 protein: a molecular dynamics approach
Cited by: 45
Author(s): C. George Priya Doss, N. Nagasundaram, Chiranjib Chakraborty, Luonan Chen, Hailong Zhu
Software Mentions: 1
Published: over 11 years ago

10.1186/1479-7364-6-10

Conservation of the three-dimensional structure in non-homologous or unrelated proteins
Cited by: 25
Author(s): Konstantinos Sousounis, Carl E Haney, Jian Cao, Bharath Sunchu, Panagiotis A. Tsonis
Software Mentions: 1
Published: over 12 years ago

10.1186/s40246-021-00351-2

Established and candidate transthyretin amyloidosis variants identified in the Saudi population by data mining
Cited by: 5
Author(s): Mohamed Abouelhoda, Dania Mohty, Islam Alayary, Brian F. Meyer, Stefan T. Arold, Bahaa M. Fadel, Dorota Monies
Software Mentions: 1
Published: over 3 years ago

10.1186/s40246-021-00345-0

ACER3-related leukoencephalopathy: expanding the clinical and imaging findings spectrum due to novel variants
Cited by: 1
Author(s): Ali Zare Dehnavi, Erfan Heidari, Maryam Rasulinezhad, Morteza Heidari, Mahmoud Reza Ashrafi, Mohammad Mehdi Hosseini, Fatemeh Sadeghzadeh, Mohammad‐Sadegh Fallah, Noushin Rostampour, Amir Bahraini, Masoud Garshasbi, Ali Reza Tavasoli
Software Mentions: 1
Published: over 3 years ago

10.1093/hmg/ddv181

A microfibril assembly assay identifies different mechanisms of dominance underlying Marfan syndrome, stiff skin syndrome and acromelic dysplasias
Cited by: 25
Author(s): Sacha A. Jensen, Saba Iqbal, Alicja Bulsiewicz, Penny A. Handford
Software Mentions: 1
Published: over 9 years ago

10.1093/hmg/ddu369

Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies
Cited by: 79
Author(s): Chie Shimamoto, Tetsuo Ohnishi, Motoko Maekawa, Akïharu Watanabe, Hideki Ohba, Ryoichi Arai, Yoshimi Iwayama, Yu Hisano, Tomoko Toyota, Manabu Toyoshima, Katsuaki Suzuki, Yukihiko Shirayama, Kazuhiko Nakamura, Norio Mori, Yuji Owada, Tetsuyuki Kobayashi, Takeo Yoshikawa
Software Mentions: 1
Published: over 10 years ago

10.1093/hmg/ddu360

Phenotypic severity of homozygous GCK mutations causing neonatal or childhood-onset diabetes is primarily mediated through effects on protein stability
Cited by: 38
Author(s): Anne Raimondo, Ali J. Chakera, Soren K. Thomsen, Kevin Colclough, Amy Barrett, Elisa De Franco, Alisson Chatelas, Hüseyin Demirbilek, Teoman Akçay, Hussein Alawneh, Sarah E. Flanagan, Martijn van de Bunt, Andrew T. Hattersley, Anna L. Gloyn, Sian Ellard, Mohammad A. Abduljabbar, Mahmoud Alzyoud, Syed Aman, Louise Bath, Parijat De, Neeta Deshpande, Erdem Durmaz, Frank Eickmeier, Nancy Samir Elbarbary, Marc Fillion, Sujatha Jagadeesh, Melanie Kershaw, Waqas Imran Khan, Wojciech Młynarski, Kathryn Noyes, Catherine Peters, Nick Shaw, Irina Tiron, Doğa Türkkahraman, Lesley Turner, Khadiga Eltonbary, Bilgin Yüksel
Software Mentions: 1
Published: over 10 years ago

10.1093/hmg/ddt535

Absence of cell surface expression of human ACE leads to perinatal death
Cited by: 13
Author(s): Annie Michaud, K. Ravi Acharya, Geoffrey Masuyer, Nicole Quenech’Du, Olivier Gribouval, Vincent Morinière, Marie–Claire Gubler, Pierre Corvol
Software Mentions: 1
Published: about 11 years ago

10.1002/humu.24210

Bi‐allelic <i>KARS1</i> pathogenic variants affecting functions of cytosolic and mitochondrial isoforms are associated with a progressive and multisystem disease
Cited by: 7
Author(s): Gerarda Cappuccio, Camilla Ceccatelli Berti, Enrico Baruffini, Jennifer Sullivan, Vandana Shashi, Tamison Jewett, Tara H. Stamper, Silvia Maitz, Francesco Canonico, Anya Revah‐Politi, Gabriel Kupchik, Kwame Anyane‐Yeboa, Vimla S. Aggarwal, Andreas Benneche, Eirik Bratland, Siren Berland, Felice D’Arco, César Augusto Pinheiro Ferreira Alves, Adeline Vanderver, Daniela Longo, Enrico Bertini, Annalaura Torella, Vincenzo Nigro, Alessandra D’Amico, Marjo S. van der Knaap, P Goffrini, Nicola Brunetti‐Pierri
Software Mentions: 1
Published: over 3 years ago

10.1002/humu.23975

Genetic and phenotypic spectrum associated with IFIH1 gain‐of‐function
Cited by: 59
Author(s): Gillian I. Rice, Sehoon Park, Francesco Gavazzi, Laura Adang, Loveline A Ayuk, Lien Van Eyck, Luis Seabra, Christophe Barrea, Roberta Battini, Alexandre Belot, Stefan Berg, Thierry Billette de Villemeur, Annette Bley, Lubov Blumkin, Odile Boespflug‐Tanguy, Tracy A Briggs, Elise Brimble, Russell C. Dale, Niklas Darín, François-Guillaume Debray, Valentina De Giorgis, Jonas Denecke, Diane Doummar, Gunilla Drake Af Hagelsrum, Despina Eleftheriou, Margherita Estienne, Elisa Fazzi, François Feillet, Jessica Galli, Nicholas Hartog, Julie Harvengt, Bénédicte Héron, Delphine Héron, Diedre A Kelly, Dorit Lev, Virginie Levrat, John H. Livingston, Itxaso Martí, Cyril Mignot, Fanny Mochel, Marie‐Christine Nouguès, Ilena Oppermann, Belén Pérez‐Dueñas, Bernt Popp, Mathieu P Rodero, Diana Rodriguez, Veronica Saletti, Cia Sharpe, Davide Tonduti, Gayatri Vadlamani, Keith Van Haren, Miguel Tomás Vila, Julie Vogt, Evangeline Wassmer, Arnaud Wiedemann, Callum Wilson, Ayelet Zerem, Christiane Zweier, Sameer M. Zuberi, Simona Orcesi, Adeline Vanderver, Sun Hur, Yanick J. Crow
Software Mentions: 1
Published: almost 5 years ago

10.1002/humu.23949

Congenital myasthenic syndrome due to mutations in <i>MUSK</i> suggests that the level of MuSK phosphorylation is crucial for governing synaptic structure
Cited by: 17
Author(s): Pedro M. Rodríguez Cruz, Judy Cossins, Jonathan Cheung, Susan Maxwell, Sandeep Jayawant, Ruth Herbst, Dominic Waithe, Alexandr P. Kornev, Jackie Palace, David Beeson
Software Mentions: 1
Published: almost 5 years ago

10.1038/s41396-020-00758-0

A 500-year tale of co-evolution, adaptation, and virulence: Helicobacter pylori in the Americas
Cited by: 18
Author(s): Zilia Y Muñoz-Ramirez, Ben Pascoe, Alfonso Méndez‐Tenorio, Evangelos Mourkas, Santiago Sandoval-Motta, Guillermo I. Perez-Perez, Douglas R. Morgan, Ricardo L. Domínguez, Diana Ortiz-Princz, María Eugenia Cavazza, Gifone A. Rocha, Dulcienne M. M. Queiroz, Mariana Catalano, Gerardo Zerbeto De La Palma, Cinthia G. Goldman, Alejandro Venegas, Teresa Alarcón, Mónica Oleastro, Filipa F. Vale, Karen J. Goodman, Roberto Torres, Elvire Berthenet, Matthew D. Hitchings, Martin J. Blaser, Samuel K. Sheppard, Kaisa Thorell, Javier Torres
Software Mentions: 1
Published: about 4 years ago

10.1155/2013/185807

Molecular Characterization and Phylogenetic Analysis of a Histone-Derived Antimicrobial Peptide Teleostin from the Marine Teleost Fishes, <i>Tachysurus jella</i> and <i>Cynoglossus semifasciatus</i>
Cited by: 14
Author(s): E. R. Chaithanya, Rosamma Philip, Naveen Sathyan, Praveen Kumar
Software Mentions: 1
Published: over 11 years ago

10.5402/2012/481539

Structural Modeling and Analysis of Pregnancy-Associated Glycoprotein-1 of Buffalo (Bubalus bubalis)
Cited by: 2
Author(s): Jerome Andonissamy, SK Singh, SK Agarwal
Software Mentions: 1
Published: over 12 years ago

10.5402/2012/219656

Identification and Molecular Characterization of Molluskin, a Histone-H2A-Derived Antimicrobial Peptide from Molluscs
Cited by: 25
Author(s): Naveen Sathyan, Rosamma Philip, E. R. Chaithanya, Praveen Kumar
Software Mentions: 1
Published: about 12 years ago

10.1155/2013/930216

Characterization of Histone H2A Derived Antimicrobial Peptides, Harriottins, from Sicklefin Chimaera <i>Neoharriotta pinnata</i> (Schnakenbeck, 1931) and Its Evolutionary Divergence with respect to CO1 and Histone H2A
Cited by: 10
Author(s): Naveen Sathyan, Rosamma Philip, E. R. Chaithanya, Praveen Kumar, V. N. Sanjeevan, I. S. Bright Singh
Software Mentions: 1
Published: over 11 years ago

10.1002/iub.2439

<scp><i>Vibrio cholerae</i></scp> biofilm scaffolding protein <scp>RbmA</scp> shows an intrinsic, phosphate‐dependent autoproteolysis activity
Cited by: 1
Author(s): M. Maestre-Reyna, Weicheng Huang, Wen‐Jin Wu, Praveen Singh, Raimo Hartmann, Po‐Hsun Wang, Cheng‐Chung Lee, Takaaki Hikima, Masaki Yamamoto, Yoshitaka Bessho, Knut Drescher, Max Tsai, Andrew H.‐J. Wang
Software Mentions: 1
Published: almost 4 years ago

10.1107/S2052252514023306

Data to knowledge: how to get meaning from your result
Cited by: 12
Author(s): Helen M. Berman, Margaret Gabanyi, Colin R. Groom, John E. Johnson, Garib N. Murshudov, Robert A. Nicholls, Vijay Reddy, Torsten Schwede, Matthew D. Zimmerman, John D. Westbrook, Władek Minor
Software Mentions: 1
Published: almost 10 years ago

10.1107/S2052252516002487

Structures of<i>C</i>-mannosylated anti-adhesives bound to the type 1 fimbrial FimH adhesin
Cited by: 15
Author(s): Jérôme de Ruyck, Marc F. Lensink, Julie Bouckaert
Software Mentions: 1
Published: over 8 years ago

10.1107/S2052252519015409

Structural and kinetic insights into flavin-containing monooxygenase and calponin-homology domains in human MICAL3
Cited by: 10
Author(s): Junsoo Kim, Haemin Lee, Yeon Jin Roh, Han Ul Kim, Dongsuk Shin, Sorah Kim, Jonghyeon Son, Aro Lee, Minseo Kim, Junga Park, Seong-Yun Hwang, Kyung-Hwan Kim, Yong Kwon Lee, Hyun Suk Jung, Kwang Yeon Hwang, Byeong Cheol Lee
Software Mentions: 1
Published: almost 5 years ago

10.1107/S2052252520003917

A structural study of TatD from <i>Staphylococcus aureus</i> elucidates a putative DNA-binding mode of a Mg²⁺-dependent nuclease
Cited by: 3
Author(s): Kyu‐Yeon Lee, Seung‐Ho Cheon, Dong-Gyun Kim, Sang Jae Lee, Bong-Jin Lee
Software Mentions: 1
Published: over 4 years ago

10.1107/S2052252518012459

Structures of collagen IV globular domains: insight into associated pathologies, folding and network assembly
Cited by: 12
Author(s): Patricia Casino, Roberto Gozalbo-Rovira, Jesús Rodrı́guez-Dı́az, Sreedatta Banerjee, Ariel Boutaud, Vicente Rubio, Billy G. Hudson, Juan Saus, Javier Cervera, Alberto Marina
Software Mentions: 1
Published: about 6 years ago

10.1107/S2052252520015675

Insights into the structure of mature streptavidin C1 from Streptomyces cinnamonensis reveal the self-binding of the extension C-terminal peptide to biotin-binding sites
Cited by: 2
Author(s): Byeong Jun Jeon, Sulhee Kim, Minseok Kim, Ji-Ho Lee, Beom Seok Kim, Kwang Yeon Hwang
Software Mentions: 1
Published: almost 4 years ago

10.1107/S2052252515019971

Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization
Cited by: 14
Author(s): Yi Tian Ting, Patricia M. Harris, Gaëlle Batot, Margaret A. Brimble, Edward N. Baker, Paul G. Young
Software Mentions: 1
Published: almost 9 years ago

10.1107/S2052252517000367

The mechanism behind the selection of two different cleavage sites in NAG-NAM polymers
Cited by: 10
Author(s): Marko Mihelič, Kristina Vlahoviček-Kahlina, M. Renko, Michael P. Williamson, Andreja Doberšek, Ajda Taler‐Verčič, Andreja Jakas, Dušan Turk
Software Mentions: 1
Published: almost 8 years ago

10.1107/S2052252520011288

An automated platform for <i>in situ</i> serial crystallography at room temperature
Cited by: 6
Author(s): Zhong Ren, Cong Wang, Heewhan Shin, Sepalika Bandara, Indika Kumarapperuma, Michael Y Ren, Weijia Kang, Xiaojing Yang
Software Mentions: 1
Published: about 4 years ago

10.1107/S2052252520009446

Protein–lipid architecture of a cholinergic postsynaptic membrane
Cited by: 18
Author(s): Nigel Unwin
Software Mentions: 1
Published: over 4 years ago

10.1107/S2052252520003632

Crystal structure of the NS3-like helicase from Alongshan virus
Cited by: 10
Author(s): Xiaopan Gao, Keqing Zhu, Justyna Aleksandra Wojdyla, Pu Chen, Bo Qin, Ziheng Li, Meitian Wang, Sheng Cui
Software Mentions: 1
Published: over 4 years ago

10.1107/S205225251901073X

Conformational characterization of full-length X-chromosome-linked inhibitor of apoptosis protein (XIAP) through an integrated approach
Cited by: 4
Author(s): Panagis Polykretis, Enrico Luchinat, Alessio Bonucci, Andrea Giachetti, Melissa A. Graewert, Dmitri I. Svergun, Lucia Banci
Software Mentions: 1
Published: over 5 years ago

10.1107/S205225252100275X

Crystal structures of Aspergillus oryzae Rib2 deaminase: the functional mechanism involved in riboflavin biosynthesis
Cited by: 2
Author(s): Sheng-Chia Chen, Li-Ci Ye, Te-Ming Yen, Ruei-Xin Zhu, Chengyu Li, San-Chi Chang, Shwu-Jen Liaw, Chun‐Hua Hsu
Software Mentions: 1
Published: over 3 years ago

10.1107/S2052252515002146

SFX analysis of non-biological polycrystalline samples
Cited by: 6
Author(s): Tao Zhang, Shifeng Jin, Yongqi Gu, Yao He, Ming Li, Li Yang, Hong-Yi Fan
Software Mentions: 1
Published: over 9 years ago

10.1107/S2052252514016741

New structural forms of a mycobacterial adenylyl cyclase Rv1625c
Cited by: 6
Author(s): D.V. Barathy, Rohini Mattoo, Sandhya S. Visweswariah, K. Suguna
Software Mentions: 1
Published: over 10 years ago

10.1107/S205225251901707X

Structural insights into conformational switching in latency-associated peptide between transforming growth factor β-1 bound and unbound states
Cited by: 5
Author(s): Timothy R. Stachowski, M. Elizabeth Snell, Edward H. Snell
Software Mentions: 1
Published: almost 5 years ago

10.1107/S2052252520000986

Structure and mechanism of copper–carbonic anhydrase II: a nitrite reductase
Cited by: 15
Author(s): Jacob T. Andring, Chae Un Kim, Robert McKenna
Software Mentions: 1
Published: almost 5 years ago

10.1107/S2052252517007527

Active-site protein dynamics and solvent accessibility in native<i>Achromobacter cycloclastes</i>copper nitrite reductase
Cited by: 10
Author(s): Kakali Sen, Sam Horrell, D. Kekilli, Chin W. Yong, Thomas W. Keal, Hakan Atakişi, David Moreau, Robert Thorne, Michael A. Hough, R.W. Strange
Software Mentions: 1
Published: over 7 years ago

10.1107/S2052252521004826

The mechanism driving a solid–solid phase transition in a biomacromolecular crystal
Cited by: 2
Author(s): Saminathan Ramakrishnan, Jason R. Stagno, William F. Heinz, Xiaobing Zuo, Ping Yü, Yun‐Xing Wang
Software Mentions: 1
Published: over 3 years ago

10.1107/S2052252515000238

Structure of a 13-fold superhelix (almost) determined from first principles
Cited by: 4
Author(s): Guillaume A. Schoch, Massimo Sammito, Claudia Millán, Isabel Usón, M.G. Rudolph
Software Mentions: 1
Published: almost 10 years ago

10.1107/S2052252521005704

Crystal structure of a MarR family protein from the psychrophilic bacterium <i>Paenisporosarcina</i> sp. TG-14 in complex with a lipid-like molecule
Cited by: 2
Author(s): Jisub Hwang, Sunha Park, Chang Woo Lee, Hackwon Do, Seung Chul Shin, Han-Woo Kim, Sung Gu Lee, Hyun Ho Park, Sunghoon Kwon, Jun Hyuck Lee
Software Mentions: 1
Published: about 3 years ago

10.1107/S2052252521005613

Conformational flexibility of EptA driven by an interdomain helix provides insights for enzyme–substrate recognition
Cited by: 5
Author(s): Anandhi Anandan, Nicholas W Dunstan, Timothy M. Ryan, Haydyn D. T. Mertens, Katherine Y L Lim, G.L. Evans, Charlene M. Kahler, Alice Vrielink
Software Mentions: 1
Published: over 3 years ago

10.1107/S2052252520015614

Crystal structure of death-associated protein kinase 1 in complex with the dietary compound resveratrol
Cited by: 8
Author(s): Takeshi Yokoyama, Ryoya Suzuki, Mineyuki Mizuguchi
Software Mentions: 1
Published: almost 4 years ago

10.1107/S2052252517017626

Active-site solvent replenishment observed during human carbonic anhydrase II catalysis
Cited by: 12
Author(s): Jin Kyun Kim, Carrie L. Lomelino, Balendu Sankara Avvaru, Brian P. Mahon, Robert McKenna, SangYoun Park, Chae Un Kim
Software Mentions: 1
Published: almost 7 years ago

10.1107/S2052252520003656

The active form of quinol-dependent nitric oxide reductase from <i>Neisseria meningitidis</i> is a dimer
Cited by: 9
Author(s): M. Arif M. Jamali, Chai Gopalasingam, Rachel M. Johnson, Takehiko Tosha, Kazumasa Muramoto, Stephen P. Muench, S.V. Antonyuk, Yoshitsugu Shiro, S.S. Hasnain
Software Mentions: 1
Published: over 4 years ago

10.7554/eLife.58128

Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity
Cited by: 5
Author(s): Juan L. Mendoza, Suzanne Fischer, Marvin H. Gee, Lilian H. Lam, Simon Brackenridge, Fiona Powrie, Michael E. Birnbaum, Andrew J. McMichael, K. Christopher García, Geraldine M. Gillespie
Software Mentions: 1
Published: over 4 years ago

10.7554/eLife.00691

Phosphorylation-mediated PTEN conformational closure and deactivation revealed with protein semisynthesis
Cited by: 87
Author(s): David M. Bolduc, Meghdad Rahdar, Becky Tu-Sekine, Sindhu Carmen Sivakumaren, Daniel M. Raben, L. Mario Amzel, Peter N. Devreotes, Sandra B. Gabelli, Philip A. Cole
Software Mentions: 1
Published: over 11 years ago

10.7554/eLife.67622

Distinct expression requirements and rescue strategies for BEST1 loss- and gain-of-function mutations
Cited by: 9
Author(s): Qingqing Zhao, Yang Kong, Alec Kittredge, Yao Li, Yin Shen, Yu Zhang, Stephen H. Tsang, Tingting Yang
Software Mentions: 1
Published: over 3 years ago

10.7554/eLife.28086

The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere
Cited by: 59
Author(s): Gemma Lm Fisher, César L. Pastrana, Victoria Ann Higman, Alan Koh, James Taylor, Annika Butterer, Timothy D. Craggs, Frank Sobott, Heath Murray, Matthew P. Crump, Fernando Moreno‐Herrero, Mark S. Dillingham
Software Mentions: 1
Published: almost 7 years ago

10.7554/eLife.41803

ATP-induced asymmetric pre-protein folding as a driver of protein translocation through the Sec machinery
Cited by: 30
Author(s): Robin A. Corey, Zainab Ahdash, Anokhi Shah, Euan Pyle, William J. Allen, Tomáš Fessl, Janet E. Lovett, Argyris Politis, Ian Collinson
Software Mentions: 1
Published: almost 6 years ago

10.7554/eLife.13405

Molecular mechanism of activation-triggered subunit exchange in Ca2+/calmodulin-dependent protein kinase II
Cited by: 86
Author(s): Moitrayee Bhattacharyya, Margaret M. Stratton, Catherine C. Going, Ethan D. McSpadden, Yongjian Huang, Anna C. Susa, Anna V. Elleman, Yumeng Cao, Nishant Pappireddi, Pawel Burkhardt, Christine L. Gee, Tiago Barros, Howard Schulman, Evan R. Williams, John Kuriyan
Software Mentions: 1
Published: over 8 years ago

10.7554/eLife.55943

A single power stroke by ATP binding drives substrate translocation in a heterodimeric ABC transporter
Cited by: 30
Author(s): Erich Stefan, Susanne Hofmann, Robert Tampé
Software Mentions: 1
Published: over 4 years ago

10.7554/eLife.34995

Structural basis of malodour precursor transport in the human axilla
Cited by: 33
Author(s): G.S. Minhas, Daniel Bawdon, Reyme Herman, Michelle Rudden, Abraham Stone, A. Gordon James, Gavin H. Thomas, Simon Newstead
Software Mentions: 1
Published: over 6 years ago

10.7554/eLife.35957

Functional trade-offs and environmental variation shaped ancient trajectories in the evolution of dim-light vision
Cited by: 17
Author(s): Gianni M Castiglione, Belinda S. W. Chang
Software Mentions: 1
Published: about 6 years ago

10.7554/eLife.65822

Voltage-clamp fluorometry analysis of structural rearrangements of ATP-gated channel P2X2 upon hyperpolarization
Cited by: 5
Author(s): Rizki Tsari Andriani, Yoshihiro Kubo
Software Mentions: 1
Published: over 3 years ago

10.7554/eLife.68215

The neuronal calcium sensor Synaptotagmin-1 and SNARE proteins cooperate to dilate fusion pores
Cited by: 21
Author(s): Zhenyong Wu, Nadiv Dharan, Zachary A. McDargh, Sathish Thiyagarajan, Ben O’Shaughnessy, Erdem Karatekin
Software Mentions: 1
Published: over 3 years ago

10.7554/eLife.01519

Mechanism of chiral proofreading during translation of the genetic code
Cited by: 38
Author(s): Sadeem Ahmad, Satya Brata Routh, Venu Kamarthapu, Jisha Chalissery, Sowndarya Muthukumar, Tanweer Hussain, Shobha P Kruparani, Mandar V. Deshmukh, Rajan Sankaranarayanan
Software Mentions: 1
Published: almost 11 years ago

10.7554/eLife.64922

A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations
Cited by: 8
Author(s): Jone Paesmans, Ella Martin, Babette Deckers, Marjolijn Berghmans, Ritika Sethi, Yannick Loeys, Els Pardon, Jan Steyaert, Patrik Verstreken, Christian Galicia, Wim Versées
Software Mentions: 1
Published: almost 4 years ago

10.7554/eLife.37122

BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions
Cited by: 35
Author(s): Nicolas Béry, A. Cruz-Migoni, Carole J. R. Bataille, Camilo Quevedo, Hanna Tulmin, Arthur I. Miller, Angela J. Russell, Simon E. V. Phillips, S.B. Carr, Terence H. Rabbitts
Software Mentions: 1
Published: over 6 years ago

10.7554/eLife.51162

Protein polyglutamylation catalyzed by the bacterial calmodulin-dependent pseudokinase SidJ
Cited by: 50
Author(s): Alan Sulpizio, Marena E. Minelli, Min Wan, Paul d. Burrowes, Xiaochun Wu, Ethan J. Sanford, Jung-Ho Shin, Byron Williams, Michael L. Goldberg, Marcus B. Smolka, Yuxin Mao
Software Mentions: 1
Published: about 5 years ago

10.7554/eLife.41103

Activation mechanism of ATP-sensitive K+ channels explored with real-time nucleotide binding
Cited by: 27
Author(s): Michael C. Puljung, Natascia Vedovato, Samuel Usher, Frances M. Ashcroft
Software Mentions: 1
Published: almost 6 years ago

10.7554/eLife.64415

On the emergence of P-Loop NTPase and Rossmann enzymes from a Beta-Alpha-Beta ancestral fragment
Cited by: 55
Author(s): Liam M. Longo, Jagoda Jabłońska, Pratik Vyas, Manil Kanade, Rachel Kolodny, Nir Ben‐Tal, Dan S. Tawfik
Software Mentions: 1
Published: almost 4 years ago

10.7554/eLife.47150

Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics
Cited by: 25
Author(s): Shannon N. Mostyn, Katie A. Wilson, Alexandra Schumann-Gillett, Zachary J. Frangos, Susan Shimmon, Tristan Rawling, Renae M. Ryan, Megan L. O’Mara, Robert J. Vandenberg
Software Mentions: 1
Published: about 5 years ago

10.7554/eLife.34843

Mechano-redox control of integrin de-adhesion
Cited by: 44
Author(s): Freda Passam, Joyce Chiu, Lining Arnold Ju, Aster E. Pijning, Zeenat Jahan, Ronit Mor‐Cohen, Adva Yeheskel, Katra Kolšek, Lena Thärichen, Camilo Aponte-Santamaría, Frauke Gräter, Philip J. Hogg
Software Mentions: 1
Published: over 6 years ago

10.7554/eLife.45801

Near-infrared dual bioluminescence imaging in mouse models of cancer using infraluciferin
Cited by: 44
Author(s): Cassandra Stowe, Thomas A. Burley, H. R. Allan, Maria Vinci, Gabriela Kramer‐Marek, Daniela M. Ciobota, Gary N. Parkinson, Tara L. Southworth, Giulia Agliardi, Alastair Hotblack, Mark F. Lythgoe, Bruce R. Branchini, Tammy L. Kalber, James C. Anderson, Martin Pulé
Software Mentions: 1
Published: about 5 years ago

10.7554/eLife.59520

Identification of specific Tie2 cleavage sites and therapeutic modulation in experimental sepsis
Cited by: 7
Author(s): Temitayo O. Idowu, Valerie Etzrodt, Benjamin Seeliger, Patricia Bolaños-Palmieri, Kristina Thamm, Hermann Haller, Sascha David
Software Mentions: 1
Published: over 4 years ago

10.7554/eLife.15886

PtdInsP2 and PtdSer cooperate to trap synaptotagmin-1 to the plasma membrane in the presence of calcium
Cited by: 92
Author(s): Ángel Pérez-Lara, Anusa Thapa, Sarah B. Nyenhuis, David A. Nyenhuis, Partho Halder, Michael Tietzel, Kai Tittmann, David S. Cafiso, Reinhard Jahn
Software Mentions: 1
Published: about 8 years ago

10.7554/eLife.19706

Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending
Cited by: 14
Author(s): Aleksandra Bebel, Ezgi Karaca, B. Mohana Kumar, W. Marshall Stark, O. Barábas
Software Mentions: 1
Published: almost 8 years ago

10.7554/eLife.24109

Malaria parasite LIMP protein regulates sporozoite gliding motility and infectivity in mosquito and mammalian hosts
Cited by: 27
Author(s): Jorge M. Santos, Saskia Egarter, Vanessa Zuzarte‐Luís, Hirdesh Kumar, Catherine Moreau, Jessica Kehrer, Andreia Pinto, Mário da Costa, Blandine Franke-Fayard, Chris J. Janse, Friedrich Frischknecht, Gunnar R. Mair
Software Mentions: 1
Published: over 7 years ago

10.7554/eLife.56428

A mechanism for the extension and unfolding of parallel telomeric G-quadruplexes by human telomerase at single-molecule resolution
Cited by: 34
Author(s): Bishnu P. Paudel, Aaron L. Moye, Hala Abou Assi, Roberto El-Khoury, Scott B. Cohen, Jessica K. Holien, Monica L. Birrento, Siritron Samosorn, Kamthorn Intharapichai, Christopher G. Tomlinson, Marie‐Paule Teulade‐Fichou, Carlos González, Jennifer L. Beck, Masad J. Damha, Antoine M. van Oijen, Tracy M. Bryan
Software Mentions: 1
Published: over 4 years ago

10.7554/eLife.66181

Allosteric communication in DNA polymerase clamp loaders relies on a critical hydrogen-bonded junction
Cited by: 13
Author(s): Subu Subramanian, Kent Gorday, Kendra Marcus, Matthew R Orellana, Peter Ren, Xiao Ran Luo, Mike O'Donnell, John Kuriyan
Software Mentions: 1
Published: over 3 years ago

10.7554/eLife.27049

Acidic C-terminal domains autoregulate the RNA chaperone Hfq
Cited by: 53
Author(s): Andrew Santiago-Frangos, Jeliazko R. Jeliazkov, Jeffrey J. Gray, Sarah A. Woodson
Software Mentions: 1
Published: over 7 years ago

10.7554/eLife.63349

Membrane binding controls ordered self-assembly of animal septins
Cited by: 29
Author(s): Agata Szuba, Fouzia Bano, Gerard Castro-Linares, François, Manos Mavrakis, Ralf P. Richter, Aurélie Bertin, Gijsje H. Koenderink
Software Mentions: 1
Published: over 3 years ago

10.7554/eLife.49787

Formation of a β-barrel membrane protein is catalyzed by the interior surface of the assembly machine protein BamA
Cited by: 40
Author(s): James Lee, David Tomasek, Thiago M. A. Santos, Mary D. May, Ina Meuskens, Daniel Kahne
Software Mentions: 1
Published: about 5 years ago

10.7554/eLife.40789

Cryptic genetic variation shapes the adaptive evolutionary potential of enzymes
Cited by: 33
Author(s): Florian Baier, Nansook Hong, Yang Guolin, Anna Pabis, C.M. Miton, Alexandre Barrozo, P.D. Carr, Shina Caroline Lynn Kamerlin, Colin J. Jackson, Nobuhiko Tokuriki
Software Mentions: 1
Published: almost 6 years ago

10.7554/eLife.03069

A tethered delivery mechanism explains the catalytic action of a microtubule polymerase
Cited by: 91
Author(s): Pelin Ayaz, Sarah Munyoki, Elisabeth A. Geyer, Felipe Andrés Piedra, Emily S. Vu, Raquel Bromberg, Zbyszek Otwinowski, Nick V. Grishin, Chad A. Brautigam, Luke M. Rice
Software Mentions: 1
Published: over 10 years ago

10.7554/eLife.28409

A synaptotagmin suppressor screen indicates SNARE binding controls the timing and Ca2+ cooperativity of vesicle fusion
Cited by: 29
Author(s): Zhuo Guan, Maria Bykhovskaia, Ramón A. Jorquera, R. Bryan Sutton, Yulia Akbergenova, J Troy Littleton
Software Mentions: 1
Published: about 7 years ago

10.7554/eLife.01279

Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin
Cited by: 63
Author(s): Yuxiao Wang, Heath G. Pascoe, Chad A. Brautigam, Huawei He, Xuewu Zhang
Software Mentions: 1
Published: about 11 years ago

10.7554/eLife.22175

Changes in the free-energy landscape of p38α MAP kinase through its canonical activation and binding events as studied by enhanced molecular dynamics simulations
Cited by: 60
Author(s): Antonija Kuzmanic, Ludovico Sutto, Giorgio Saladino, Angel R. Nebreda, Francesco Luigi Gervasio, Modesto Orozco
Software Mentions: 1
Published: over 7 years ago

10.7554/eLife.41604

Molecular basis for activation of lecithin:cholesterol acyltransferase by a compound that increases HDL cholesterol
Cited by: 32
Author(s): Kelly A. Manthei, Shyh Ming Yang, Bolormaa Baljinnyam, Louise Chang, Alisa Glukhova, Wenjie Yuan, Lita A. Freeman, David J. Maloney, Anna Schwendeman, Alan T. Remaley, Ajit Jadhav, John J.G. Tesmer
Software Mentions: 1
Published: almost 6 years ago

10.7554/eLife.70372

Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy
Cited by: 24
Author(s): Lisa M Strong, Chunmei Chang, Julia F Riley, C. Alexander Boecker, Thomas G Flower, Cosmo Z. Buffalo, Xuefeng Ren, Andrea K.H. Stavoe, Erika L.F. Holzbaur, James H. Hurley
Software Mentions: 1
Published: about 3 years ago

10.7554/eLife.45851

A valve-like mechanism controls desensitization of functional mammalian isoforms of acid-sensing ion channels
Cited by: 21
Author(s): Yangyu Wu, Zhuyuan Chen, Cecilia M. Canessa
Software Mentions: 1
Published: over 5 years ago

10.7554/eLife.00411

Cryo-EM visualization of the ribosome in termination complex with apo-RF3 and RF1
Cited by: 32
Author(s): Jesper Pallesen, Yaser Hashem, Gürkan Korkmaz, Ravi Kiran Koripella, Chenhui Huang, Måns Ehrenberg, Suparna Sanyal, Joachim Frank
Software Mentions: 1
Published: over 11 years ago

10.7554/eLife.42636

Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs
Cited by: 77
Author(s): David Kern, SeCheol Oh, Richard K Hite, Stephen G. Brohawn
Software Mentions: 1
Published: almost 6 years ago

10.7554/eLife.63691

Myosin with hypertrophic cardiac mutation R712L has a decreased working stroke which is rescued by omecamtiv mecarbil
Cited by: 23
Author(s): Aaron Snoberger, Bipasha Barua, Jennifer L. Atherton, Henry Shuman, Éva Forgács, Yale E. Goldman, Donald A. Winkelmann, E. Michael Ostap
Software Mentions: 1
Published: almost 4 years ago

10.7554/eLife.38356

Structural basis for Scc3-dependent cohesin recruitment to chromatin
Cited by: 61
Author(s): Yan Li, Kyle Muir, Matthew W. Bowler, J Metz, Christian H. Haering, Daniel Panne
Software Mentions: 1
Published: over 6 years ago

10.7554/eLife.35774

Metazoan evolution of glutamate receptors reveals unreported phylogenetic groups and divergent lineage-specific events
Cited by: 37
Author(s): David Ramos-Vicente, Jie Ji, Esther Gratacòs-Batlle, Gemma Gou, Rita Reig-Viader, Javier Rodríguez Luis, Demián Burguera, Enrique Navas-Pérez, Jordi García-Fernández, Pablo Fuentes‐Prior, Héctor Escrivá, Nerea Roher, David Soto, Àlex Bayés
Software Mentions: 1
Published: about 6 years ago

10.7554/eLife.04266

Antibacterial gene transfer across the tree of life
Cited by: 65
Author(s): Jason A. Metcalf, Lisa J. Funkhouser-Jones, Kristen A. Brileya, Anna‐Louise Reysenbach, Seth R. Bordenstein
Software Mentions: 1
Published: almost 10 years ago

10.7554/eLife.46840

Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B
Cited by: 29
Author(s): Timo Vögtle, Sumana Sharma, Jun Mori, Z. Nagy, Daniela Semeniak, Cyril Scandola, Mitchell J. Geer, Christopher W. Smith, Jordan Lane, Scott J. Pollack, Riitta Lassila, Annukka Jouppila, Alastair J. Barr, D. Ogg, Tina D. Howard, H.J. McMiken, Juli Warwicker, Catherine Geh, Rachel Rowlinson, W. Mark Abbott, Anita Eckly, Harald Schulze, Gavin J. Wright, Alexandra Mazharian, Klaus Fütterer, Sundaresan Rajesh, Michael E. Douglas, Yotis A. Senis
Software Mentions: 1
Published: over 5 years ago

10.7554/eLife.14107

Molecular basis for multimerization in the activation of the epidermal growth factor receptor
Cited by: 134
Author(s): Yongjian Huang, Shashank Bharill, Deepti Karandur, Sean M. Peterson, Morgan Marita, Xiaojun Shi, Megan J. Kaliszewski, Adam W. Smith, Ehud Y. Isacoff, John Kuriyan
Software Mentions: 1
Published: over 8 years ago

10.7554/eLife.45068

Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation
Cited by: 26
Author(s): Jamie A. Macpherson, Alina Theisen, Laura Masino, Louise Fets, Paul C. Driscoll, Vesela Encheva, Ambrosius P. Snijders, Stephen R. Martin, Jens Kleinjung, Perdita E. Barran, Franca Fraternali, Dimitrios Anastasiou
Software Mentions: 1
Published: over 5 years ago

10.7554/eLife.52505

Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs
Cited by: 34
Author(s): Michelle Reid, David Kern, Stephen G. Brohawn
Software Mentions: 1
Published: over 4 years ago

10.7554/eLife.38089

Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation
Cited by: 41
Author(s): Ryan Ferrao, Heidi J.A. Wallweber, P.J. Lupardus
Software Mentions: 1
Published: over 6 years ago

10.7554/eLife.53930

JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes
Cited by: 16
Author(s): Schuyler Lee, Haolin Liu, Ryan C. Hill, Chunjing Chen, Xue-Ren Hong, Frances Crawford, Molly C. Kingsley, Qianqian Zhang, Xinjian Liu, Zhongzhou Chen, Andreas Lengeling, Kathrin M. Bernt, Philippa Marrack, John W. Kappler, Qiang Zhou, Chuan-Yuan Li, Yuhua Xue, Kirk C. Hansen, Gongyi Zhang
Software Mentions: 1
Published: almost 5 years ago

10.7554/eLife.08928

Roles of the membrane-reentrant β-hairpin-like loop of RseP protease in selective substrate cleavage
Cited by: 39
Author(s): Koichiro Akiyama, Shinya Mizuno, Yohei Hizukuri, Hiroyuki Mori, Terukazu Nogi, Yoshinori Akiyama
Software Mentions: 1
Published: about 9 years ago

10.7554/eLife.70067

A universal pocket in fatty acyl-AMP ligases ensures redirection of fatty acid pool away from coenzyme A-based activation
Cited by: 7
Author(s): Gajanan S. Patil, Priyadarshan Kinatukara, Sudipta Mondal, Sakshi Shambhavi, Ketan D. Patel, Surabhi Pramanik, Noopur Dubey, Subhash Narasimhan, Murali Krishna Madduri, Biswajit Pal, Rajesh S. Gokhale, Rajan Sankaranarayanan
Software Mentions: 1
Published: about 3 years ago

10.7554/eLife.19238

Ric-8A, a G protein chaperone with nucleotide exchange activity induces long-range secondary structure changes in Gα
Cited by: 20
Author(s): Ravi Kant, Baisen Zeng, Ciza Thomas, Brian Bothner, Stephen R. Sprang
Software Mentions: 1
Published: almost 8 years ago

10.7554/eLife.11058

Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity
Cited by: 140
Author(s): Bernadette Carroll, Dorothea Maetzel, Oliver D.K. Maddocks, Elsje G. Otten, Matthew Ratcliff, Graham R. Smith, Elaine A. Dunlop, João F. Passos, Owen R. Davies, Rudolf Jaenisch, Andrew R. Tee, Sovan Sarkar, Viktor I. Korolchuk
Software Mentions: 1
Published: almost 9 years ago

10.7554/eLife.16616

The selectivity of the Na+/K+-pump is controlled by binding site protonation and self-correcting occlusion
Cited by: 26
Author(s): Huan Rui, Pablo Artigas, Benoît Roux
Software Mentions: 1
Published: over 8 years ago

10.7554/eLife.29914

Patient-specific mutations impair BESTROPHIN1’s essential role in mediating Ca2+-dependent Cl- currents in human RPE
Cited by: 43
Author(s): Yao Li, Yu Zhang, Yu Xu, Alec Kittredge, Nancy E. Ward, Shoudeng Chen, Stephen H. Tsang, Tingting Yang
Software Mentions: 1
Published: about 7 years ago