Ecosyste.ms: Papers
An open API service providing mapping between scientific papers and software projects that are mentioned in them.
All mentions data is based on the CZI Software Mentions dataset.
Projects: pypi: PARS
https://packages.ecosyste.ms/registries/pypi.org/packages/PARS
Project which enable automatic downloading data from pfam and rfam databases
2 versions
Latest release: about 3 years ago
44 downloads last month
Papers Mentioning PARS 73
10.1186/s13059-019-1641-3
dStruct: identifying differentially reactive regions from RNA structurome profiling dataCited by: 20
Author(s): Krishna Choudhary, Yi-Chun Lai, Elizabeth Tran, Sharon Aviran
Software Mentions: 8
Published: almost 6 years ago
10.7554/eLife.39054
New insights into the cellular temporal response to proteostatic stressCited by: 40
Author(s): Justin Rendleman, Zhe Cheng, Shuvadeep Maity, Nicolai Kastelic, Mathias Munschauer, Kristina Allgoewer, Guoshou Teo, Yun Bin Matteo Zhang, Amy Lei, Brian J. Parker, Markus Landthaler, Lindsay Freeberg, Scott Kuersten, Hyungwon Choi, Christine Vogel
Software Mentions: 5
Published: about 6 years ago
10.3389/fgene.2017.00147
An Algorithm for Template-Based Prediction of Secondary Structures of Individual RNA SequencesCited by: 2
Author(s): Josef Pánek, Martin Modrák, Marek Schwarz
Software Mentions: 5
Published: about 7 years ago
10.1186/s12859-019-2645-4
reactIDR: evaluation of the statistical reproducibility of high-throughput structural analyses towards a robust RNA structure predictionCited by: 5
Author(s): Risa Karakida Kawaguchi, Hisanori Kiryu, Junichi Iwakiri, Jun Sese
Software Mentions: 5
Published: over 5 years ago
10.3390/genes9060300
Automated Recognition of RNA Structure Motifs by Their SHAPE Data SignaturesCited by: 10
Author(s): Pierce Radecki, Mirko Ledda, Sharon Aviran
Software Mentions: 3
Published: over 6 years ago
10.3390/genes12020187
Genomics Insights into Pseudomonas sp. CG01: An Antarctic Cadmium-Resistant Strain Capable of Biosynthesizing CdS Nanoparticles Using Methionine as S-SourceCited by: 3
Author(s): Carla Gallardo-Benavente, Jessica L. Campo-Giraldo, Juan Castro‐Severyn, Andrés Quiróz, José M. Pérez-Donoso
Software Mentions: 3
Published: almost 4 years ago
10.1371/journal.pone.0183859
Genome sequences of lower Great Lakes Microcystis sp. reveal strain-specific genes that are present and expressed in western Lake Erie bloomsCited by: 35
Author(s): Kevin A. Meyer, Timothy W. Davis, Susan B. Watson, Vincent J. Denef, Michelle A. Berry, Gregory J. Dick
Software Mentions: 3
Published: about 7 years ago
10.1186/s12864-021-07638-7
Structural landscape of the complete genomes of dengue virus serotypes and other viral hemorrhagic feversCited by: 5
Author(s): Riccardo Delli Ponti, Marek Mutwil
Software Mentions: 3
Published: over 3 years ago
10.3389/fnins.2020.569517
Dissecting Neuronal Activation on a Brain-Wide Scale With Immediate Early GenesCited by: 25
Author(s): Alessandra Franceschini, Irene Costantini, Francesco S. Pavone, Ludovico Silvestri
Software Mentions: 3
Published: about 4 years ago
10.1111/jcmm.13238
State of the art technologies to explore long non-coding RNAs in cancerCited by: 57
Author(s): Saeede Salehi, Mohammad Taheri, Negar Azarpira, Abdolhossein Zare, Abbas Behzad-Behbahani
Software Mentions: 3
Published: over 7 years ago
10.1371/journal.pone.0189389
PARS risk charts: A 10-year study of risk assessment for cardiovascular diseases in Eastern Mediterranean RegionCited by: 24
Author(s): Nizal Sarrafzadegan, Razieh Hassannejad, Hamid Reza Marateb, Mohammad Talaei, Masoumeh Sadeghi, Hamidreza Roohafza, Farzad Masoudkabir, Shahram Oveisgharan, Marjan Mansourian, Mohammad Reza Mohebian, Miguel Ángel Mañanas
Software Mentions: 2
Published: almost 7 years ago
10.3390/ijms20225610
Secondary Structural Model of Human MALAT1 Reveals Multiple Structure–Function RelationshipsCited by: 38
Author(s): Phillip J. McCown, Matthew C. Wang, Luc Jaeger, Jessica A. Brown
Software Mentions: 2
Published: about 5 years ago
10.3390/metabo3020259
Getting Your Peaks in Line: A Review of Alignment Methods for NMR Spectral DataCited by: 93
Author(s): Trung Nghia Vu, Kris Laukens
Software Mentions: 2
Published: over 11 years ago
10.1186/s12859-016-1071-0
A comprehensive database of high-throughput sequencing-based RNA secondary structure probing data (Structure Surfer)Cited by: 15
Author(s): Nathan D. Berkowitz, Ian M. Silverman, Daniel Micah Childress, Hilal Kazan, Li-San Wang, Brian D. Gregory
Software Mentions: 2
Published: over 8 years ago
10.3390/ijms22158252
Revisiting the Proposition of Binding Pockets and Bioactive Poses for GSK-3β Allosteric Modulators Addressed to Neurodegenerative DiseasesCited by: 6
Author(s): Guilherme M. Silva, Rosivaldo S. Borges, Kelton L. B. Santos, Leonardo Bruno Federico, Isaque Antônio Galindo Francischini, Suzane Quintana Gomes, Mariana Pegrucci Barcelos, Raí C. Silva, Cleydson Breno Rodrigues dos Santos, Carlos Henrique Tomich de Paula da Silva
Software Mentions: 2
Published: over 3 years ago
10.1007/s10928-020-09685-1
Enabling pregnant women and their physicians to make informed medication decisions using artificial intelligenceCited by: 25
Author(s): Lena Davidson, Mary Regina Boland
Software Mentions: 2
Published: over 4 years ago
10.3389/fpubh.2020.00257
Functionality of Physical Activity Referral Schemes (PARS): A Systematic ReviewCited by: 11
Author(s): Francis A. Albert, Melissa Crowe, A.E.O. Malau‐Aduli, Bunmi S. Malau‐Aduli
Software Mentions: 2
Published: over 4 years ago
10.1186/s12864-018-4497-0
RNA secondary structure profiling in zebrafish reveals unique regulatory featuresCited by: 9
Author(s): Kriti Kaushik, Ambily Sivadas, Shamsudheen Karuthedath Vellarikkal, Ankit Verma, Rijith Jayarajan, Satyaprakash Pandey, Tavpritesh Sethi, Souvik Maiti, Vinod Scaria, Sridhar Sivasubbu
Software Mentions: 2
Published: almost 7 years ago
10.1186/s12859-016-1067-9
Parallel computation of genome-scale RNA secondary structure to detect structural constraints on human genomeCited by: 28
Author(s): Risa Karakida Kawaguchi, Hisanori Kiryu
Software Mentions: 2
Published: over 8 years ago
10.3389/fmicb.2018.00828
The Genomic Basis of Intrinsic and Acquired Antibiotic Resistance in the Genus SerratiaCited by: 43
Author(s): Luisa Sandner-Miranda, Pablo Vinuesa, Alejandro Cravioto, Rosario Morales-Espinosa
Software Mentions: 2
Published: over 6 years ago
10.3389/fmolb.2020.586544
Analyzing In Silico the Relationship Between the Activation of the Edema Factor and Its Interaction With CalmodulinCited by: 0
Author(s): Irène Pitard, Damien Monet, Pierre L. Goossens, Arnaud Blondel, Thérèse E. Malliavin
Software Mentions: 2
Published: almost 4 years ago
10.3390/s20195595
A Review of Endogenous and Exogenous Contrast Agents Used in Photoacoustic Tomography with Different Sensing ConfigurationsCited by: 27
Author(s): Victor T. C. Tsang, Xiufeng Li, Terence T. W. Wong
Software Mentions: 2
Published: about 4 years ago
10.3389/fmolb.2021.666626
Computational Identification of a Putative Allosteric Binding Pocket in TMPRSS2Cited by: 3
Author(s): Jacopo Sgrignani, Andrea Cavalli
Software Mentions: 2
Published: over 3 years ago
10.1016/j.str.2017.01.008
Predicting Protein Dynamics and Allostery Using Multi-Protein Atomic Distance ConstraintsCited by: 40
Author(s): Joe G Greener, Ioannis Filippis, Michael J.E. Sternberg
Software Mentions: 2
Published: over 7 years ago
10.3390/ijerph15112452
PARS: Using Augmented 360-Degree Panoramas of Reality for Construction Safety TrainingCited by: 78
Author(s): Ricardo Eiris, Masoud Gheisari, Behzad Esmaeili
Software Mentions: 2
Published: about 6 years ago
10.1371/journal.pgen.1005233
The 4E-BP Caf20p Mediates Both eIF4E-Dependent and Independent Repression of TranslationCited by: 36
Author(s): Lydia M. Castelli, David Talavera, Christopher J. Kershaw, Sarah S. Mohammad‐Qureshi, Joseph L. Costello, William Rowe, Paul F. G. Sims, Chris M. Grant, Simon J. Hubbard, Mark P. Ashe, Graham D. Pavitt
Software Mentions: 2
Published: over 9 years ago
10.1186/s12929-020-00640-3
Functions and properties of nuclear lncRNAs—from systematically mapping the interactomes of lncRNAsCited by: 51
Author(s): Chia-Yu Guh, Yu-Hung Hsieh, Hao-Hua Chu
Software Mentions: 1
Published: over 4 years ago
10.1371/journal.ppat.1008184
An RNA thermometer dictates production of a secreted bacterial toxinCited by: 22
Author(s): Christian Twittenhoff, Ann Kathrin Heroven, Sabrina Mühlen, Petra Dersch, Franz Narberhaus
Software Mentions: 1
Published: almost 5 years ago
10.1111/phn.12697
The development of a parental attachment recognition scale for mothers nurturing preschool childrenCited by: 1
Author(s): Yôko Tanaka
Software Mentions: 1
Published: almost 5 years ago
10.1186/s40638-018-0090-x
Cognition-based variable admittance control for active compliance in flexible manipulation of heavy objects with a power-assist robotic systemCited by: 10
Author(s): S. M. Mizanoor Rahman, Ryojun Ikeura
Software Mentions: 1
Published: about 6 years ago
10.1038/s41598-019-49849-9
All-optical Reflection-mode Microscopic Histology of Unstained Human TissuesCited by: 37
Author(s): Saad Abbasi, Martin Le, Bazil Sonier, Deepak Dinakaran, Gilbert Bigras, Kevan Bell, John R. Mackey, Parsin Haji Reza
Software Mentions: 1
Published: about 5 years ago
10.1038/s41598-020-74160-3
Improving maximal safe brain tumor resection with photoacoustic remote sensing microscopyCited by: 24
Author(s): Benjamin R. Ecclestone, Kevan Bell, Saad Abbasi, Deepak Dinakaran, Frank K.H. van Landeghem, John R. Mackey, Paul Fieguth, Parsin Haji Reza
Software Mentions: 1
Published: about 4 years ago
10.1038/s41598-020-76155-6
Reflection-mode virtual histology using photoacoustic remote sensing microscopyCited by: 24
Author(s): Kevan Bell, Saad Abbasi, Deepak Dinakaran, Muba Taher, Gilbert Bigras, Frank K.H. van Landeghem, John R. Mackey, Parsin Haji Reza
Software Mentions: 1
Published: about 4 years ago
10.1038/s41598-021-90776-5
Functional and structural ophthalmic imaging using noncontact multimodal photoacoustic remote sensing microscopy and optical coherence tomographyCited by: 21
Author(s): Zohreh Hosseinaee, Nima Abbasi, Nicholas Pellegrino, Layla Khalili, Lyazzat Mukhangaliyeva, Parsin Haji Reza
Software Mentions: 1
Published: over 3 years ago
10.1038/s41598-021-93222-8
Three-dimensional virtual histology in unprocessed resected tissues with photoacoustic remote sensing (PARS) microscopy and optical coherence tomography (OCT)Cited by: 8
Author(s): Benjamin R. Ecclestone, Zohreh Hosseinaee, Nima Abbasi, Kevan Bell, Deepak Dinakaran, John R. Mackey, Parsin Haji Reza
Software Mentions: 1
Published: over 3 years ago
10.1186/s40064-016-3076-6
The diversity of mtDNA rns introns among strains of Ophiostoma piliferum, Ophiostoma pluriannulatum and related speciesCited by: 1
Author(s): Iman M. Bilto, Georg Hausner
Software Mentions: 1
Published: over 8 years ago
10.1186/s12966-020-01050-2
A modified Delphi study to gain consensus for a taxonomy to report and classify physical activity referral schemes (PARS)Cited by: 16
Author(s): Coral L Hanson, Emily J. Oliver, Caroline J. Dodd-Reynolds, Alice Pearsons, Paul Kelly
Software Mentions: 1
Published: almost 4 years ago
10.3390/ijerph17186832
Green Health Partnerships in Scotland; Pathways for Social Prescribing and Physical Activity ReferralCited by: 14
Author(s): Sheona McHale, Alice Pearsons, Lis Neubeck, Coral L Hanson
Software Mentions: 1
Published: about 4 years ago
10.3390/ijerph18062957
Understanding Leisure Centre-Based Physical Activity after Physical Activity Referral: Evidence from Scheme Participants and Completers in Northumberland UKCited by: 3
Author(s): Jordan Bell, Lis Neubeck, Kai Jin, Paul Kelly, Coral L Hanson
Software Mentions: 1
Published: over 3 years ago
10.3390/ijms141223672
Tackling Structures of Long Noncoding RNAsCited by: 68
Author(s): Irina Novikova, Scott P. Hennelly, Karissa Y. Sanbonmatsu
Software Mentions: 1
Published: almost 11 years ago
10.3390/ijms17050702
Understanding the Functions of Long Non-Coding RNAs through Their Higher-Order StructuresCited by: 70
Author(s): Rui Li, Hongliang Zhu, Yane Luo
Software Mentions: 1
Published: over 8 years ago
10.3390/ijms21093099
Structural and Evolutionary Analysis Indicate That the SARS-CoV-2 Mpro Is a Challenging Target for Small-Molecule Inhibitor DesignCited by: 128
Author(s): Maria Bzówka, Karolina Mitusińska, Agata Raczyńska, Aleksandra Samol, Jack A. Tuszyński, Artur Góra
Software Mentions: 1
Published: over 4 years ago
10.3390/ijms22010187
Dynamical Correlations Reveal Allosteric Sites in G Protein-Coupled ReceptorsCited by: 5
Author(s): Pedro Renault, Jesús Giraldo
Software Mentions: 1
Published: almost 4 years ago
10.3390/ijms22105108
Some Dietary Phenolic Compounds Can Activate Thyroid Peroxidase and Inhibit Lipoxygenase-Preliminary Study in the Model SystemsCited by: 6
Author(s): Ewa Habza-Kowalska, Agnieszka A. Kaczor, Damian Bartuzi, Jacek Piłat, Urszula Gawlik‐Dziki
Software Mentions: 1
Published: over 3 years ago
10.3390/ijms22136730
Can Developments in Tissue Optical Clearing Aid Super-Resolution Microscopy Imaging?Cited by: 0
Author(s): Paweł Matryba, Kacper Łukasiewicz, Monika Pawłowska, Jacek Tomczuk, Jakub Goła̧b
Software Mentions: 1
Published: over 3 years ago
10.1136/jnnp-2015-311890
The prediagnostic phase of Parkinson's diseaseCited by: 116
Author(s): Alastair Noyce, Andrew J. Lees, Anette-Eleonore Schrag
Software Mentions: 1
Published: almost 9 years ago
10.1155/2016/3136024
In Silico Approach for SAR Analysis of the Predicted Model of DEPDC1B: A Novel Target for Oral CancerCited by: 10
Author(s): Palak Ahuja, K. N. Singh
Software Mentions: 1
Published: over 8 years ago
10.1155/2021/5541753
Schisandrol A Attenuates Myocardial Ischemia/Reperfusion-Induced Myocardial Apoptosis through Upregulation of 14-3-3θCited by: 8
Author(s): Shuaishuai Gong, Jincheng Liu, Shi-Yao Wan, Weiwei Yang, Yuanyuan Zhang, Boyang Yu, Fang Li, Junping Kou
Software Mentions: 1
Published: over 3 years ago
10.1186/1471-2105-14-269
Efficient alignment of RNA secondary structures using sparse dynamic programmingCited by: 9
Author(s): Cuncong Zhong, Shaojie Zhang
Software Mentions: 1
Published: about 11 years ago
10.1186/1471-2105-15-S9-S15
ProbeAlign: incorporating high-throughput sequencing-based structure probing information into ncRNA homology searchCited by: 3
Author(s): Peng Ge, Cuncong Zhong, Shaojie Zhang
Software Mentions: 1
Published: about 10 years ago
10.1186/s12859-015-0771-1
AlloPred: prediction of allosteric pockets on proteins using normal mode perturbation analysisCited by: 78
Author(s): Joe G Greener, Michael J.E. Sternberg
Software Mentions: 1
Published: about 9 years ago
10.1186/1471-2105-11-470
Trees on networks: resolving statistical patterns of phylogenetic similarities among interacting proteinsCited by: 5
Author(s): William N. Kelly, Michael Stumpf
Software Mentions: 1
Published: about 14 years ago
10.1186/s12861-014-0048-3
Improved application of the electrophoretic tissue clearing technology, CLARITY, to intact solid organs including brain, pancreas, liver, kidney, lung, and intestineCited by: 67
Author(s): Hyunsu Lee, Jae-Hyung Park, Incheol Seo, Sun-Hyun Park, Shin Kim
Software Mentions: 1
Published: almost 10 years ago
10.1186/1471-2164-12-532
Within-species lateral genetic transfer and the evolution of transcriptional regulation in Escherichia coli and ShigellaCited by: 27
Author(s): Elizabeth Skippington, Mark A. Ragan
Software Mentions: 1
Published: about 13 years ago
10.1186/1471-2164-8-154
Highly asymmetric rice genomesCited by: 36
Author(s): Jing Ding, Hideki Araki, Qiang Wang, Pengfei Zhang, Sihai Yang, Jian-Qun Chen, Dacheng Tian
Software Mentions: 1
Published: over 17 years ago
10.1186/1471-2334-7-98
Association of Escherichia coli O157:H7 tirpolymorphisms with human infectionCited by: 74
Author(s): James L. Bono, James E. Keen, Marion Clawson, Lisa M. Durso, Michael P. Heaton, William W. Laegreid
Software Mentions: 1
Published: over 17 years ago
10.1186/s12884-018-1973-0
Perinatal death beyond 41 weeks pregnancy: an evaluation of causes and substandard care factors as identified in perinatal audit in the NetherlandsCited by: 15
Author(s): Joep C. Kortekaas, Anke C. Scheuer, Esteriek de Miranda, Aimée E. van Dijk, Judit K. J. Keulen, Aafke Bruinsma, Ben Willem J. Mol, Frank P.H.A. Vandenbussche, Jeroen van Dillen
Software Mentions: 1
Published: about 6 years ago
10.1186/1752-0509-1-1
Evolutionary conservation and over-representation of functionally enriched network patterns in the yeast regulatory networkCited by: 36
Author(s): Ofer Meshi, Tomer Shlomi, Eytan Ruppin
Software Mentions: 1
Published: almost 18 years ago
10.1080/21655979.2017.1373537
Bioengineering of crop plants for improved tetrahydrofolate productionCited by: 3
Author(s): Bhupendra Chaudhary, Nagendra Singh, Dhananjay Pandey
Software Mentions: 1
Published: about 7 years ago
10.3390/molecules24152766
Thyroid Peroxidase Activity is Inhibited by Phenolic Compounds—Impact of InteractionCited by: 13
Author(s): Ewa Habza-Kowalska, Agnieszka A. Kaczor, Justyna Żuk, Dariusz Matosiuk, Urszula Gawlik‐Dziki
Software Mentions: 1
Published: over 5 years ago
10.13918/j.issn.2095-8137.2017.004
Does mRNA structure contain genetic information for regulating co-translational protein folding?Cited by: 3
Author(s): Jinfu Yang
Software Mentions: 1
Published: almost 8 years ago
10.1016/j.pacs.2019.100141
Review on practical photoacoustic microscopyCited by: 179
Author(s): Seungwan Jeon, Jongbeom Kim, Dong-Hyun Lee, Jin Woo Baik, Chulhong Kim
Software Mentions: 1
Published: about 5 years ago
10.1371/journal.pgen.1005613
Secondary Structure across the Bacterial Transcriptome Reveals Versatile Roles in mRNA Regulation and FunctionCited by: 167
Author(s): Cristian Del Campo, Alexander Bartholomäus, Ivan Fedyunin, Zoya Ignatova
Software Mentions: 1
Published: about 9 years ago
10.1371/journal.pgen.1001064
Ancient Protostome Origin of Chemosensory Ionotropic Glutamate Receptors and the Evolution of Insect Taste and OlfactionCited by: 603
Author(s): Vincent Croset, Raphael Rytz, Scott F. Cummins, Aidan Budd, David Brawand, Henrik Kaessmann, Toby J. Gibson, Richard Benton
Software Mentions: 1
Published: over 14 years ago
10.1371/journal.pone.0173023
The impact of RNA secondary structure on read start locations on the Illumina sequencing platformCited by: 9
Author(s): Adam Price, Jaishree Garhyan, Cynthia Gibas
Software Mentions: 1
Published: over 7 years ago
10.1371/journal.pone.0041318
Mycobacterium tuberculosis Population in Northwestern Russia: An Update from Russian-EU/Latvian Border RegionCited by: 35
Author(s): Igor Mokrousov, Anna Vyazovaya, Tatiana Otten, Viacheslav Zhuravlev, Еlena Pavlova, Larisa Tarashkevich, Valery Krishevich, Boris Vishnevsky, Olga Narvskaya
Software Mentions: 1
Published: over 12 years ago
10.1371/journal.pone.0137078
Helicobacter pylori bab Paralog Distribution and Association with cagA, vacA, and homA/B Genotypes in American and South Korean Clinical IsolatesCited by: 19
Author(s): Aeryun Kim, Stephanie L. Servetas, Jieun Kang, Jinmoon Kim, Sungil Jang, Jin Huang, Wan Jin Lee, June Kim, Judith Romero–Gallo, Richard M. Peek, D. Scott Merrell, Jeong Heon
Software Mentions: 1
Published: about 9 years ago
10.22074/cellj.2019.5684
A Simple Technique for Three-Dimensional Imaging and Segmentation of Brain Vasculature U sing Fast Free-of-Acrylamide Clearing Tissue in Murine.Cited by: 7
Author(s): Arezoo Khoradmehr, Fahime Mazaheri, Morteza Anvari, Amin Tamadon
Software Mentions: 1
Published: over 5 years ago
10.1007/s00259-021-05270-x
Just another “Clever Hans”? Neural networks and FDG PET-CT to predict the outcome of patients with breast cancerCited by: 23
Author(s): Manuel Weber, David Kersting, Lale Umutlu, Michael Schäfers, Christoph Rischpler, Wolfgang P. Fendler, Irène Buvat, Ken Herrmann, Robert Seifert
Software Mentions: 1
Published: over 3 years ago
10.3389/fmed.2021.628179
Evaluation of an Automatic Classification Algorithm Using Convolutional Neural Networks in Oncological Positron Emission TomographyCited by: 19
Author(s): Pierre Pinochet, Florian Eude, Stéphanie Becker, Vijay Shah, Ludovic Sibille, Mathieu Nessim Toledano, Romain Modzelewski, Pierre Véra, Pierre Decazes
Software Mentions: 1
Published: over 3 years ago
10.3389/fpls.2018.00671
New Era of Studying RNA Secondary Structure and Its Influence on Gene Regulation in PlantsCited by: 27
Author(s): Xiaofei Yang, Minglei Yang, Huiyong Deng, Yiliang Ding
Software Mentions: 1
Published: over 6 years ago
10.1117/1.JBO.26.5.056007
Single acquisition label-free histology-like imaging with dual-contrast photoacoustic remote sensing microscopyCited by: 5
Author(s): Benjamin R. Ecclestone, Deepak Dinakaran, Parsin Haji Reza
Software Mentions: 1
Published: over 3 years ago
10.1117/1.JBO.26.6.069801
Single acquisition label-free histology-like imaging with dual-contrast photoacoustic remote sensing microscopy (Errata)Cited by: 1
Author(s): Benjamin R. Ecclestone, Deepak Dinakaran, Parsin Haji Reza
Software Mentions: 1
Published: over 3 years ago