pypi: LDpred | Projects | Ecosyste.ms: Papers

10.1038/s41598-017-13056-1

A machine-learning heuristic to improve gene score prediction of polygenic traits
Cited by: 63
Author(s): Guillaume Paré, Mao S, Wei Q. Deng
Software Mentions: 6
Published: about 7 years ago

A fast and robust Bayesian nonparametric method for prediction of complex traits using summary statistics
Cited by: 27
Author(s): Geyu Zhou, Hongyu Zhao
Software Mentions: 5
Published: over 3 years ago

10.1007/s10519-019-09951-0

A Genetic Investigation of the Well-Being Spectrum
Cited by: 35
Author(s): Bart M. L. Baselmans, Margot P van de Weijer, Abdel Abdellaoui, Jacqueline M. Vink, Jouke Jan Hottenga, Gonneke Willemsen, Michel G. Nivard, Eco J. C. de Geus, Dorret I. Boomsma, Meike Bartels
Software Mentions: 4
Published: almost 6 years ago

10.1371/journal.pone.0200785

Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture
Cited by: 125
Author(s): Stuart K. Kim
Software Mentions: 4
Published: over 6 years ago

10.1093/bioinformatics/btaa1029

LDpred2: better, faster, stronger
Cited by: 212
Author(s): Florian Privé, Julyan Arbel, Bjarni J. Vilhjálmsson
Software Mentions: 4
Published: about 4 years ago

10.3389/fpsyt.2021.688464

Predicting Complex Traits and Exposures From Polygenic Scores and Blood and Buccal DNA Methylation Profiles
Cited by: 10
Author(s): Veronika V. Odintsova, Valerie Rebattu, Fiona A. Hagenbeek, René Pool, Jeffrey J. Beck, Erik A. Ehli, Catharina E. M. van Beijsterveldt, Lannie Ligthart, Gonneke Willemsen, Eco J. C. de Geus, Jouke Jan Hottenga, Dorret I. Boomsma, Jenny van Dongen
Software Mentions: 3
Published: over 3 years ago

10.1371/journal.pgen.1008202

Exploring various polygenic risk scores for skin cancer in the phenomes of the Michigan genomics initiative and the UK Biobank with a visual catalog: PRSWeb
Cited by: 27
Author(s): Lars G. Fritsche, Lauren J. Beesley, Peter VandeHaar, Robert B. Peng, Maxwell Salvatore, Matthew Zawistowski, Sarah A. Gagliano Taliun, Das S, Jonathon LeFaive, Erin O. Kaleba, Thomas T. Klumpner, Stephanie Moser, Victoria M. Blanc, Chad M. Brummett, Sachin Kheterpal, Gonçalo R. Abecasis, Stephen B. Gruber, Bhramar Mukherjee
Software Mentions: 3
Published: over 5 years ago

10.1371/journal.pgen.1009021

Evaluation of polygenic prediction methodology within a reference-standardized framework
Cited by: 84
Author(s): Oliver Pain, Kylie P. Glanville, Saskia P. Hagenaars, Saskia Selzam, Anna E. Fürtjes, Héléna A. Gaspar, Jonathan R. I. Coleman, Kaili Rimfeld, Gerome Breen, Robert Plomin, Lasse Folkersen, Cathryn M. Lewis
Software Mentions: 3
Published: over 3 years ago

10.1016/j.cell.2021.07.038

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations
Cited by: 151
Author(s): Cindy G. Boer, Konstantinos Hatzikotoulas, Lorraine Southam, Lilja Stefánsdóttir, Yanfei Zhang, Rodrigo Coutinho de Almeida, Tian Wu, Jie Zheng, April Hartley, Maris Teder‐Laving, Anne Heidi Skogholt, Chikashi Terao, Eleni Zengini, G Alexiadis, Andrei Barysenka, Gyða Björnsdóttir, Maiken Elvestad Gabrielsen, Arthur Gilly, Þorvaldur Ingvarsson, Marianne Bakke Johnsen, Helgi Jónsson, Margreet Kloppenburg, Almut Luetge, Sigrún H. Lund, Reedik Mägi, Massimo Mangino, Rob R.G.H.H. Nelissen, Manu Shivakumar, Julia Steinberg, Hiroshi Takuwa, Laurent F. Thomas, Margo Tuerlings, Hunt All-In Pain, George C. Babis, Jason Pui Yin Cheung, Jae H. Kang, Peter Kraft, Steven A. Lietman, Dino Samartzis, P. Eline Slagboom, Kāri Stefánsson, Unnur Þorsteinsdóttir, Jonathan H Tobias, André G. Uitterlinden, Bendik S. Winsvold, John‐Anker Zwart, George Davey Smith, Pak C. Sham, Guðmar Þorleifsson, Tom R. Gaunt, Andrew P. Morris, Ana M. Valdes, Aspasia Tsezou, Kathryn S.E. Cheah, Shiro Ikegawa, Kristian Hveem, Tõnu Esko, J. Mark Wilkinson, Ingrid Meulenbelt, Ming Ta Michael Lee, Joyce B. J. van Meurs, Unnur Styrkársdóttir, Eleftheria Zeggini
Software Mentions: 3
Published: over 3 years ago

10.1001/jamaophthalmol.2019.4421

Association Between Polygenic Risk Score and Risk of Myopia
Cited by: 40
Author(s): Neema Ghorbani Mojarrad, Denis Plotnikov, Cathy Williams, Jeremy A. Guggenheim
Software Mentions: 2
Published: almost 5 years ago

10.1038/srep41262

Improving polygenic risk prediction from summary statistics by an empirical Bayes approach
Cited by: 43
Author(s): Hon‐Cheong So, Pak C. Sham
Software Mentions: 2
Published: almost 8 years ago

10.1093/gigascience/giz082

PRSice-2: Polygenic Risk Score software for biobank-scale data
Cited by: 813
Author(s): Shing Wan Choi, Paul F. O’Reilly
Software Mentions: 2
Published: over 5 years ago

10.1371/journal.pone.0255348

Polygenic scores for smoking and educational attainment have independent influences on academic success and adjustment in adolescence and educational attainment in adulthood
Cited by: 3
Author(s): Brian M. Hicks, David A. Clark, Joseph D. Deak, Jonathan D. Schaefer, Mengzhen Liu, Seon-Kyeong Jang, C. Emily Durbin, Wendy Johnson, Sylia Wilson, William G. Iacono, Matt McGue, Scott Vrieze
Software Mentions: 2
Published: over 3 years ago

10.1371/journal.pcbi.1005589

Leveraging functional annotations in genetic risk prediction for human complex diseases
Cited by: 122
Author(s): Yiming Hu, Qiongshi Lu, Ryan L. Powles, Xinwei Yao, Can Yang, Fang Fang, Xinran Xu, Hongyu Zhao
Software Mentions: 2
Published: over 7 years ago

10.3389/fgene.2021.632385

An Improved Genome-Wide Polygenic Score Model for Predicting the Risk of Type 2 Diabetes
Cited by: 17
Author(s): Wei Liu, Zhenhuang Zhuang, Wenxiu Wang, Tao Huang, Liu Z
Software Mentions: 2
Published: almost 4 years ago

10.1038/s42003-020-01334-0

The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study
Cited by: 62
Author(s): Yu‐Fang Pei, Yaozhong Liu, Xiaolin Yang, Lei Zhang, Guoliang Feng, Xin‐Tong Wei
Software Mentions: 2
Published: about 4 years ago

10.1111/jcpp.13113

The p factor: genetic analyses support a general dimension of psychopathology in childhood and adolescence
Cited by: 110
Author(s): Andrea G. Allegrini, Rosa Cheesman, Kaili Rimfeld, Saskia Selzam, Jean‐Baptiste Pingault, Thalia C. Eley, Robert Plomin
Software Mentions: 2
Published: over 5 years ago

10.3390/genes12070991

Machine Learning Prediction of Biomarkers from SNPs and of Disease Risk from Biomarkers in the UK Biobank
Cited by: 11
Author(s): Erik Widén, Timothy G. Raben, Louis Lello, Stephen Hsu
Software Mentions: 2
Published: over 3 years ago

10.1038/s41398-020-01121-9

Genome-wide association study of pediatric obsessive-compulsive traits: shared genetic risk between traits and disorder
Cited by: 20
Author(s): Christie L. Burton, Mathieu Lemire, Bowei Xiao, Elizabeth Corfield, Lauren Erdman, Janita Bralten, Geert Poelmans, Dongmei Yu, S‐M Shaheen, Tara Goodale, Vanessa M. Sinopoli, Noam Soreni, Gregory L. Hanna, Kate D. Fitzgerald, David Rosenberg, Gerald Nestadt, Andrew D. Paterson, Lisa J. Strug, Russell Schachar, Jennifer Crosbie, Paul Arnold
Software Mentions: 1
Published: almost 4 years ago

10.1016/j.ajhg.2019.06.006

Comparing Within- and Between-Family Polygenic Score Prediction
Cited by: 174
Author(s): Saskia Selzam, Stuart J. Ritchie, Jean‐Baptiste Pingault, Chandra A. Reynolds, Paul O’Reilly, Robert Plomin
Software Mentions: 1
Published: over 5 years ago

10.1167/iovs.61.11.7

Effect of Education on Myopia: Evidence from the United Kingdom ROSLA 1972 Reform
Cited by: 19
Author(s): Denis Plotnikov, Cathy Williams, Denize Atan, Neil M Davies, Neema Ghorbani Mojarrad, Jeremy A. Guggenheim
Software Mentions: 1
Published: over 4 years ago

10.1186/s12881-020-01068-0

Ancestry effects on type 2 diabetes genetic risk inference in Hispanic/Latino populations
Cited by: 16
Author(s): Aroon T. Chande, Lavanya Rishishwar, Andrew B. Conley, Augusto Valderrama-Aguirre, Miguel A Medina-Rivas, I. King Jordan
Software Mentions: 1
Published: over 4 years ago

10.1007/s10519-015-9735-5

Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium
Cited by: 170
Author(s): Stéphanie Martine van den Berg, Marleen H. M. de Moor, Karin J. H. Verweij, Robert F. Krueger, Michelle Luciano, Alejandro Arias Vasquez, Lindsay Matteson, Jaime Derringer, Tõnu Esko, Najaf Amin, Scott D. Gordon, Narelle K. Hansell, Amy Hart, Ilkka Seppälä, Jennifer E. Huffman, Bettina Konte, Jari Lahti, Minyoung Lee, Mike Miller, Teresa Nutile, Toshiko Tanaka, Alexander Teumer, Alexander Viktorin, Juho Wedenoja, Abdel Abdellaoui, Gonçalo R. Abecasis, Daniel E. Adkins, Arpana Agrawal, Jueri Allik, Katja Appel, Timothy B. Bigdeli, Fabio Busonero, Harry Campbell, Paul T. Costa, George Davey Smith, Gail Davies, Harriet de Wit, Jun Ding, Barbara E. Engelhardt, Johan G. Eriksson, Iryna O. Fedko, Luigi Ferrucci, Barbara Franke, Ina Giegling, Richard A. Grucza, Annette M. Hartmann, Andrew C. Heath, Kati Heinonen, Anjali K. Henders, Georg Homuth, Jouke‐Jan Hottenga, William G. Iacono, J.G.E. Janzing, Markus Jokela, Robert Karlsson, John P. Kemp, Matthew G. Kirkpatrick, Antti Latvala, Terho Lehtimäki, David C. Liewald, Pamela A. F. Madden, Chiara Magri, Patrik K. E. Magnusson, Jonathan Marten, Andrea Maschio, Hamdi Mbarek, Sarah E. Medland, Evelin Mihailov, Yuri Milaneschi, Grant W. Montgomery, Matthias Nauck, Michel G. Nivard, Klaasjan G. Ouwens, Aarno Palotie, Erik Pettersson, Ozren Polašek, Yong Qian, Laura Pulkki‐Råback, Olli T. Raitakari, Anu Realo, Richard J. Rose, Daniela Ruggiero, Carsten Oliver Schmidt, Wendy S. Slutske, Rossella Sorice, John M. Starr, Beaté St Pourcain, Angelina R. Sutin, Nicholas J. Timpson, Holly Trochet, Sita H. Vermeulen, Eero Vuoksimaa, Elisabeth Widén, Jasper Wouda, Margaret J. Wright, Lina Zgaga, David J. Porteous, Alessandra Minelli, Abraham A. Palmer, Dan Rujescu, Marina Ciullo, Caroline Hayward, Igor Rudan, Andres Metspalu, Jaakko Kaprio, Ian J. Deary, Katri Räikkönen, James F. Wilson, Liisa Keltikangas‐Järvinen, Laura J. Bierut, John M. Hettema, Hans J. Grabe, Brenda W. J. H. Penninx, Cornelia M. van Duijn, David M. Evans, David Schlessinger, Nancy L. Pedersen, Antonio Terracciano, Matt McGue, Nicholas G. Martin, Dorret I. Boomsma
Software Mentions: 1
Published: over 9 years ago

10.1007/s10519-020-09992-w

Intergenerational Transmission of Education and ADHD: Effects of Parental Genotypes
Cited by: 40
Author(s): Eveline L. de Zeeuw, Jouke‐Jan Hottenga, Klaasjan G. Ouwens, Conor V. Dolan, Erik A. Ehli, Gareth E. Davies, Dorret I. Boomsma, Elsje van Bergen
Software Mentions: 1
Published: almost 5 years ago

10.1186/s13058-020-01260-3

Clinical applications of polygenic breast cancer risk: a critical review and perspectives of an emerging field
Cited by: 89
Author(s): Tatiane Yanes, Mary‐Anne Young, Bettina Meiser, Paul James
Software Mentions: 1
Published: almost 5 years ago

10.1186/s12933-020-0988-9

Polygenic risk for coronary heart disease acts through atherosclerosis in type 2 diabetes
Cited by: 21
Author(s): Tianyuan Lu, Vincenzo Forgetta, Oriana Hoi Yun Yu, Lauren Mokry, Madeline Gregory, George Thanassoulis, Celia Greenwood, J. Brent Richards
Software Mentions: 1
Published: almost 5 years ago

10.1038/s41380-020-0697-5

Genomic analysis of diet composition finds novel loci and associations with health and lifestyle
Cited by: 65
Author(s): S. Fleur W. Meddens, Ronald de Vlaming, Peter N. Bowers, Casper A.P. Burik, Richard Karlsson Linnér, Chan Wook Lee, Aysu Okbay, Patrick Turley, Cornelius A. Rietveld, Mark Alan Fontana, Mohsen Ghanbari, Fumiaki Imamura, George McMahon, Peter J. van der Most, Trudy Voortman, Kaitlin H Wade, Emma L Anderson, Kim Braun, Pauline M Emmett, Tõnu Esko, Juan R. González, Jessica C. Kiefte–de Jong, Claudia Langenberg, Jian’an Luan, Taulant Muka, Susan M. Ring, Fernando Rivadeneira, Harold Snieder, Frank J.A. van Rooij, Bruce H. R. Wolffenbuttel, George Davey Smith, Oscar H. Franco, Nita G. Forouhi, M. Arfan Ikram, André G. Uitterlinden, Jana V. van Vliet-Ostaptchouk, Nick Wareham, David Cesarini, K. Paige Harden, James J. Lee, Daniel J. Benjamin, Carson C. Chow, Philipp Koellinger
Software Mentions: 1
Published: over 4 years ago

10.1038/mp.2017.163

Multi-polygenic score approach to trait prediction
Cited by: 147
Author(s): Eva Krapohl, Hamel Patel, Stephen Newhouse, Charles Curtis, Sophie von Stumm, Philip S. Dale, Delilah Zabaneh, Gerome Breen, Paul O’Reilly, Robert Plomin
Software Mentions: 1
Published: over 7 years ago

10.1111/desc.12925

Predicting educational achievement from genomic measures and socioeconomic status
Cited by: 48
Author(s): Sophie von Stumm, Emily Smith‐Woolley, Ziada Ayorech, Andrew McMillan, Kaili Rimfeld, Philip S. Dale, Robert Plomin
Software Mentions: 1
Published: about 5 years ago

10.1534/g3.120.401658

Polygenic Scores for Height in Admixed Populations
Cited by: 70
Author(s): Bárbara Domingues Bitarello, Iain Mathieson
Software Mentions: 1
Published: about 4 years ago

10.1002/gepi.22245

A flexible and parallelizable approach to genome‐wide polygenic risk scores
Cited by: 29
Author(s): Paul Newcombe, Christopher P. Nelson, Nilesh J. Samani, Frank Dudbridge
Software Mentions: 1
Published: over 5 years ago

10.1186/s13073-021-00831-z

Development of genome-wide polygenic risk scores for lipid traits and clinical applications for dyslipidemia, subclinical atherosclerosis, and diabetes cardiovascular complications among East Asians
Cited by: 14
Author(s): Claudia H.T. Tam, Cadmon K.P. Lim, Andrea Luk, Alex Ng, Heung‐Man Lee, Guozhi Jiang, Eric S.H. Lau, Baoqi Fan, Raymond Wan, Alice P.S. Kong, Wing-Hung Tam, Risa Ozaki, Elaine Chow, Ka-Fai Lee, SC Siu, Grace Hui, Chiu-Chi Tsang, Kam-Piu Lau, Jason C. S. Leung, Man-Wo Tsang, Grace Kam, Ip Tim Lau, June K.Y. Li, Ming Wai Yeung, Emmy Lau, Stanley Lo, Samuel Fung, Yuk Lun Cheng, Chun‐Chung Chow, Miao Hu, Weichuan Yu, Stephen Kwok‐Wing Tsui, Yü Huang, Hui‐Yao Lan, Cheuk‐Chun Szeto, Nelson L. S. Tang, Maggie C. Y. Ng, Wing–Yee So, Brian Tomlinson, Juliana C.N. Chan, C. Ronald
Software Mentions: 1
Published: almost 4 years ago

10.1017/S0033291717002318

Embracing polygenicity: a review of methods and tools for psychiatric genetics research
Cited by: 67
Author(s): Robert Maier, Peter M. Visscher, Matthew R. Robinson, Naomi R. Wray
Software Mentions: 1
Published: over 7 years ago

10.1017/S0033291720000100

Measurement and genetic architecture of lifetime depression in the Netherlands as assessed by LIDAS (Lifetime Depression Assessment Self-report)
Cited by: 3
Author(s): Iryna O. Fedko, Jouke Jan Hottenga, Quinta Helmer, Hamdi Mbarek, Floris Huider, Najaf Amin, Joline W.J. Beulens, Marijke A. Bremmer, Petra Elders, Tessel E. Galesloot, Lambertus A. Kiemeney, Hanna M. van Loo, H. Susan J. Picavet, Femke Rutters, Ashley van der Spek, Anne M. van de Wiel, Cornelia M. van Duijn, Eco J. C. de Geus, Edith J. M. Feskens, Catharina A. Hartman, Albertine J. Oldehinkel, Jan Smit, W. M. Monique Verschuren, Brenda W.J.H. Penninx, Dorret I. Boomsma, Mariska Bot
Software Mentions: 1
Published: almost 5 years ago

10.1038/s41598-020-65360-y

Fine-tuning of Genome-Wide Polygenic Risk Scores and Prediction of Gestational Diabetes in South Asian Women
Cited by: 21
Author(s): Amel Lamri, Mao S, Dipika Desai, Milan Gupta, Guillaume Paré, Sonia S. Anand
Software Mentions: 1
Published: over 4 years ago

10.1038/s41598-021-90045-5

Greater genetic risk for adult psychiatric diseases increases vulnerability to adverse outcome after preterm birth
Cited by: 0
Author(s): Harriet Cullen, Saskia Selzam, Konstantina Dimitrakopoulou, Robert Plomin, A. David Edwards
Software Mentions: 1
Published: over 3 years ago

10.1038/s41398-019-0554-y

A role for vitamin D and omega-3 fatty acids in major depression? An exploration using genomics
Cited by: 30
Author(s): Yuri Milaneschi, Wouter J. Peyrot, Michel G. Nivard, Hamdi Mbarek, Dorret I. Boomsma, Brenda W. J. H. Penninx
Software Mentions: 1
Published: over 5 years ago

10.1038/s41398-019-0635-y

Novel genome-wide associations for anhedonia, genetic correlation with psychiatric disorders, and polygenic association with brain structure
Cited by: 50
Author(s): Joey Ward, Laura Lyall, Richard A. I. Bethlehem, Amy Ferguson, Rona J. Strawbridge, Breda Cullen, Nicholas Graham, Keira J.A. Johnston, Mark E.S. Bailey, Graham K. Murray, Daniel J. Smith
Software Mentions: 1
Published: about 5 years ago

Projects: pypi: LDpred

Papers Mentioning LDpred 38