Projects: cran: PHENIX

https://packages.ecosyste.ms/registries/cran.r-project.org/packages/PHENIX

Phenotypic Integration Index
7 versions
Latest release: about 9 years ago
1 dependent package
161 downloads last month

Science Score: 75/100
Starting Score: 100 points
Penalties:
  • -15 No science keywords
    No scientific terms found in keywords/classifiers
  • -10 No science terms in description
    No scientific terms found in description

Very Likely Science (75)

Papers Mentioning PHENIX 2,287

10.1371/journal.ppat.1003754
The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies
Cited by: 165
Author(s): Devin Sok, Uri Laserson, Jonathan Laserson, Yiping Liu, François Vigneault, Jean-Philippe Julien, Bryan Briney, Alejandra Ramos, Karen Saye, Khoa Le, Alison E. Mahan, Shenshen Wang, Mehran Kardar, Gur Yaari, Laura M. Walker, Birgitte B. Simen, Elizabeth St. John, Po-Ying Chan-Hui, Kristine M. Swiderek, Stephen H. Kleinstein, Galit Alter, Michael S. Seaman, Arup K. Chakraborty, Daphne Koller, Ian A. Wilson, George M. Church, Dennis R. Burton, Pascal Poignard
Software Mentions: 3
Published: over 12 years ago
10.7554/eLife.60552
Cryo-EM analysis of PIP2 regulation in mammalian GIRK channels
Cited by: 43
Author(s): Yiming Niu, Xiao Tao, Kouki K Touhara, Roderick MacKinnon
Software Mentions: 3
Published: almost 6 years ago
10.3390/ijms22168631
The Oxoglutarate Binding Site and Regulatory Mechanism Are Conserved in Ammonium Transporter Inhibitors GlnKs from Methanococcales
Cited by: 5
Author(s): Marie-Caroline Müller, T. Wagner
Software Mentions: 3
Published: about 5 years ago
10.1038/srep40517
An extended N-H bond, driven by a conserved second-order interaction, orients the flavin N5 orbital in cholesterol oxidase
Cited by: 13
Author(s): Emily Golden, Li‐Juan Yu, Flora Meilleur, Matthew P. Blakeley, Anthony P. Duff, Amir Karton, Alice Vrielink
Software Mentions: 3
Published: over 9 years ago
10.1016/j.jmb.2013.10.039
Structural Determinants of Unique Properties of Human IgG4-Fc
Cited by: 95
Author(s): Anna M. Davies, Theo Rispens, Pleuni Ooijevaar-de Heer, Hannah J. Gould, Royston Jefferis, Rob C. Aalberse, Brian J. Sutton
Software Mentions: 3
Published: over 12 years ago
10.1016/j.jmb.2015.10.027
A Substrate Mimic Allows High-Throughput Assay of the FabA Protein and Consequently the Identification of a Novel Inhibitor of Pseudomonas aeruginosa FabA
Cited by: 6
Author(s): L. Moynié, Anthony G. Hope, Kara Finzel, J.W. Schmidberger, Stuart M. Leckie, Günter Schneider, Michael D. Burkart, Andrew D. Smith, David W. Gray, James H. Naismith
Software Mentions: 3
Published: over 10 years ago
10.1016/j.jbc.2021.100700
ZapG (YhcB/DUF1043), a novel cell division protein in gamma-proteobacteria linking the Z-ring to septal peptidoglycan synthesis
Cited by: 8
Author(s): Jitender Mehla, George W. Liechti, Randy M. Morgenstein, J. Harry Caufield, Ali Hosseinnia, Alla Gagarinova, Sadhna Phanse, Norman Goodacre, Mary R. Brockett, Neha Sakhawalkar, Mohan Babu, Rong Xiao, Gaetano T. Montelione, S.M. Vorobiev, T. den Blaauwen, J.F. Hunt, Peter Uetz
Software Mentions: 3
Published: over 5 years ago
10.1098/rsob.160292
Structural, mechanistic and functional insight into gliotoxin <i>bis</i> -thiomethylation in <i>Aspergillus fumigatus</i>
Cited by: 32
Author(s): Stephen K. Dolan, Thomas Böck, Vanessa Hering, Rebecca A. Owens, Gary W. Jones, Wulf Blankenfeldt, Seán Doyle
Software Mentions: 3
Published: over 9 years ago
10.1111/cea.12230
Human <scp>I</scp> g <scp>E</scp> against the major allergen <scp>B</scp> et v 1 – defining an epitope with limited cross‐reactivity between different <scp>PR</scp> ‐10 family proteins
Cited by: 20
Author(s): Mattias Levin, Anna M. Davies, Maria Liljekvist, Fredrika Carlsson, Hannah J. Gould, Brian J. Sutton, Mats Ohlin
Software Mentions: 3
Published: over 12 years ago
10.7554/eLife.59225
Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers
Cited by: 33
Author(s): William Wan, Mairi Clarke, Michael Norris, Larissa Kolesnikova, Alexander Koehler, Zachary A. Bornholdt, Stephan Becker, Erica Ollmann Saphire, John Briggs
Software Mentions: 3
Published: almost 6 years ago
10.1016/j.jmb.2015.08.023
Atomic-Resolution Structures of the APC/C Subunits Apc4 and the Apc5 N-Terminal Domain
Cited by: 9
Author(s): Nora Cronin, Jing Yang, Ziguo Zhang, Kiran Kulkarni, Leifu Chang, Hiroyuki Yamano, David Barford
Software Mentions: 3
Published: almost 11 years ago
10.1074/jbc.M117.806893
Negatively charged residues in the first extracellular loop of the L-type CaV1.2 channel anchor the interaction with the CaVα2δ1 auxiliary subunit
Cited by: 16
Author(s): Benoîte Bourdin, Julie Briot, Marie-Philippe Tétreault, Rémy Sauvé, Lucie Parent
Software Mentions: 3
Published: almost 9 years ago
10.1016/j.jsb.2020.107545
Mitigating local over-fitting during single particle reconstruction with SIDESPLITTER
Cited by: 72
Author(s): Kailash Ramlaul, Colin M. Palmer, Takanori Nakane, C.H.S. Aylett
Software Mentions: 3
Published: about 6 years ago
10.1038/s41598-018-19991-x
Thermal stabilization of the deglycating enzyme Amadoriase I by rational design
Cited by: 18
Author(s): Federica Rigoldi, Stefano Donini, Francesca Giacomina, Federico Sorana, Alberto Redaelli, Tiziano Bandiera, Emilio Parisini, Alfonso Gautieri
Software Mentions: 3
Published: over 8 years ago
10.1074/jbc.RA119.007709
Structure and interactions of the archaeal motility repression module ArnA–ArnB that modulates archaellum gene expression in Sulfolobus acidocaldarius
Cited by: 15
Author(s): Lena Hoffmann, Katrin Anders, Lisa Franziska Bischof, Xing Ye, Julia Reimann, Sunia Khadouma, Trong Khoa Pham, Chris van der Does, Phillip C. Wright, Lars‐Oliver Essen, Sonja‐Verena Albers
Software Mentions: 3
Published: over 7 years ago
10.1038/s42003-021-02518-y
14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites
Cited by: 18
Author(s): Matej Horvath, Olívia Petrvalská, Petr Heřman, Veronika Obšilová, Tomáš Obšil
Software Mentions: 3
Published: almost 5 years ago
10.1074/jbc.RA119.010697
Structural basis of cell-surface signaling by a conserved sigma regulator in Gram-negative bacteria
Cited by: 3
Author(s): Jaime L. Jensen, Beau D. Jernberg, Sangita C. Sinha, Christopher L. Colbert
Software Mentions: 3
Published: over 6 years ago
10.7554/eLife.17903
A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading
Cited by: 32
Author(s): Chun-Min Shan, Jiyong Wang, Ke Xu, Huijie Chen, Jia-Xing Yue, Stuart Andrews, James J. Moresco, John R. Yates, Péter L. Nagy, Liang Tong, Songtao Jia
Software Mentions: 3
Published: almost 10 years ago
10.1016/j.jbc.2021.100743
From integrative structural biology to cell biology
Cited by: 38
Author(s): Andrej Šali
Software Mentions: 3
Published: over 5 years ago
10.1016/j.jbc.2021.101061
A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase
Cited by: 7
Author(s): Emily Chen, Krystle Reiss, Dilip Shah, R Manjula, Brandon Allen, Eva Murphy, James W. Murphy, Víctor S. Batista, Vineet Bhandari, Elias Lolis, George P. Lisi
Software Mentions: 3
Published: almost 5 years ago
10.1080/14756366.2021.1931862
Structure-based virtual screening of highly potent inhibitors of the nematode chitinase <i>Ce</i>Cht1
Cited by: 7
Author(s): Wei Chen, Qi Chen, Ashutosh Kumar, Xi Jiang, Kam Y. J. Zhang, Qing Yang
Software Mentions: 3
Published: over 5 years ago
10.1007/s10969-014-9188-8
Crystal structures of the S6K1 kinase domain in complexes with inhibitors
Cited by: 12
Author(s): Hideaki Niwa, Junko Mikuni, Shunta Sasaki, Yuri Tomabechi, Keiko Honda, Mariko Ikeda, Noboru Ohsawa, Motoaki Wakiyama, N. Handa, Mikako Shirouzu, Teruki Honma, Akiko Tanaka, Shigeyuki Yokoyama
Software Mentions: 3
Published: about 12 years ago
10.1038/s41598-018-21667-5
Structure based function-annotation of hypothetical protein MGG_01005 from Magnaporthe oryzae reveals it is the dynein light chain orthologue of dynlt1/3
Cited by: 2
Author(s): Guorui Li, Jinguang Huang, Jun Yang, Dan He, Chao Wang, Xiaoxuan Qi, Ian A. Taylor, Junfeng Liu, You-Liang Peng
Software Mentions: 3
Published: over 8 years ago
10.1186/s13072-016-0051-y
Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis
Cited by: 51
Author(s): Takashi Urahama, Akihito Harada, Kazuhira Maehara, Naoki Horikoshi, Koichi Sato, Yuko Sato, Koji Shiraishi, Norihiro Sugino, Akihisa Osakabe, Hiroaki Tachiwana, Wataru Kagawa, Hiroshi Kimurâ, Yasuyuki Ohkawa, Hitoshi Kurumizaka
Software Mentions: 3
Published: over 10 years ago
10.1016/j.yjsbx.2020.100031
In crystallo-screening for discovery of human norovirus 3C-like protease inhibitors
Cited by: 1
Author(s): Jingxu Guo, A. Douangamath, Weixiao Song, Alun R. Coker, A. W. Edith Chan, Steve Wood, J.B. Cooper, E. Resnick, Nir London, F. von Delft
Software Mentions: 3
Published: over 6 years ago
10.15252/embj.2018100825
Diverse roles of TssA‐like proteins in the assembly of bacterial type VI secretion systems
Cited by: 34
Author(s): Johannes Schneider, Sergey Nazarov, Ricardo Adaixo, Martina Liuzzo, Peter David Ringel, Henning Stahlberg, Marek Basler
Software Mentions: 3
Published: about 7 years ago
10.1038/s42003-021-02532-0
Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn2+ ions
Cited by: 7
Author(s): Владислав А. Лушпа, Marina V. Goncharuk, Cong Lin, Arthur O. Zalevsky, Irina A. Talyzina, Aleksandra Luginina, Daniil Vakhrameev, M.B. Shevtsov, Sergey A. Goncharuk, Alexander S. Arseniev, Valentin Borshchevskiy, Xiaohui Wang, K.S. Mineev
Software Mentions: 3
Published: almost 5 years ago
10.1038/s41422-018-0104-9
Plant HP1 protein ADCP1 links multivalent H3K9 methylation readout to heterochromatin formation
Cited by: 71
Author(s): Shuai Zhao, Lan Cheng, Yifei Gao, Baichao Zhang, Xiangdong Zheng, Liang Wang, Pilong Li, Qianwen Sun, Haitao Li
Software Mentions: 3
Published: almost 8 years ago
10.1371/journal.ppat.1002957
De novo GTP Biosynthesis Is Critical for Virulence of the Fungal Pathogen Cryptococcus neoformans
Cited by: 53
Author(s): Carl A. Morrow, Eugene Valkov, Anna Stamp, Eve W. L. Chow, I. Russel Lee, Ania Wronski, Simon J. Williams, Jennifer Hill, Julianne T. Djordjevic, Ulrike Kappler, Boštjan Kobe, James S. Fraser
Software Mentions: 3
Published: almost 14 years ago
10.7554/eLife.21646
Kinetics of the LOV domain of ZEITLUPE determine its circadian function in Arabidopsis
Cited by: 57
Author(s): Ashutosh Pudasaini, Jae Sung Shim, Young Hun Song, Hua Shi, Takatoshi Kiba, David E. Somers, Takato Imaizumi, Brian D. Zoltowski
Software Mentions: 3
Published: over 9 years ago
10.1038/s41598-017-10085-8
Intermolecular base stacking mediates RNA-RNA interaction in a crystal structure of the RNA chaperone Hfq
Cited by: 14
Author(s): Eike C. Schulz, Markus Seiler, Cecilia Zuliani, Franka Voigt, Vladimir Rybin, Vivian Pogenberg, Norbert Mücke, Matthias Wilmanns, Toby J. Gibson, O. Barábas
Software Mentions: 3
Published: almost 9 years ago
10.1128/JVI.01664-19
Structure of Merkel Cell Polyomavirus Capsid and Interaction with Its Glycosaminoglycan Attachment Receptor
Cited by: 12
Author(s): Niklas Johannes Bayer, Dovile Januliene, Georg Zocher, Thilo Stehle, Arne Moeller, Bärbel S. Blaum
Software Mentions: 3
Published: almost 6 years ago
10.1074/jbc.M117.776476
Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab
Cited by: 57
Author(s): Anna M. Davies, Elizabeth G. Allan, Anthony H. Keeble, Jean Delgado, Benjamin P. Cossins, A.N. Mitropoulou, M.O.Y. Pang, Tom Ceska, Andrew J. Beavil, Graham Craggs, Marta Westwood, Alistair J. Henry, James M. McDonnell, Brian J. Sutton
Software Mentions: 3
Published: about 9 years ago
10.1074/jbc.M115.705863
Inhibition of PRL-2·CNNM3 Protein Complex Formation Decreases Breast Cancer Proliferation and Tumor Growth
Cited by: 38
Author(s): Elie Kostantin, Serge Hardy, William C. Valinsky, Andreas Kompatscher, Jeroen H. F. de Baaij, Yevgen Zolotarov, Mélissa Landry, Noriko Uetani, Luis Alfonso Martínez-Cruz, Joost G. J. Hoenderop, Alvin Shrier, Michel L. Tremblay
Software Mentions: 3
Published: over 10 years ago
10.15252/embj.2021107985
Neutralization of SARS‐CoV‐2 by highly potent, hyperthermostable, and mutation‐tolerant nanobodies
Cited by: 56
Author(s): Thomas Güttler, Metin Aksu, Antje Dickmanns, Kim M. Stegmann, Kathrin Gregor, Renate Rees, Waltraud Taxer, Oleh Rymarenko, Jürgen Schünemann, Christian Dienemann, Philip Gunkel, Bianka Mußil, Jens Krull, Ulrike Teichmann, Uwe Groß, Volker C. Cordes, Matthias Dobbelstein, Dirk Görlich
Software Mentions: 3
Published: about 5 years ago
10.1186/s13045-020-00979-y
Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma
Cited by: 28
Author(s): Kecheng Lei, Xiaoxia Gu, Alvaro G. Alvarado, Yuhong Du, Shilin Luo, Eun Hee Ahn, Seong Su Kang, Bing Ji, Xia Liu, Hui Mao, Haian Fu, Harley I. Kornblum, Lingjing Jin, Li Hua, Keqiang Ye
Software Mentions: 3
Published: almost 6 years ago
10.1016/j.jbc.2021.100927
Beyond PKA: Evolutionary and structural insights that define a docking and dimerization domain superfamily
Cited by: 3
Author(s): Heather R. Dahlin, Ning Zheng, John D. Scott
Software Mentions: 3
Published: about 5 years ago
10.3390/ijms22083812
Crystal Structure of the Epo1-Bem3 Complex for Bud Growth
Cited by: 0
Author(s): Jin Wang, Lei Li, Zhenhua Ming, Lijie Wu, Liming Yan
Software Mentions: 3
Published: over 5 years ago
10.3390/ijms21207683
Hydroxylation of Antitubercular Drug Candidate, SQ109, by Mycobacterial Cytochrome P450
Cited by: 12
Author(s): Sergey Bukhdruker, Tatsiana Varaksa, Irina Grabovec, Egor Marin, Polina Shabunya, Maria Kadukova, Sergei Grudinin, Anton Kavaleuski, Anastasiia Gusach, Andrei A. Gilep, Valentin Borshchevskiy, Natallia Strushkevich
Software Mentions: 3
Published: almost 6 years ago
10.1038/srep33553
Crystal structures of the bifunctional tRNA methyltransferase Trm5a
Cited by: 7
Author(s): Caiyan Wang, Qian Jia, Ran Chen, Yuming Wei, Juntao Li, Jie Ma, Wei Xie
Software Mentions: 3
Published: almost 10 years ago
10.1098/rsob.160127
Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A
Cited by: 24
Author(s): Naoki Horikoshi, Yasuhiro Arimura, Hiroyuki Taguchi, Hitoshi Kurumizaka
Software Mentions: 2
Published: about 10 years ago
10.1098/rsob.160090
Structural and biochemical analyses of monoubiquitinated human histones H2B and H4
Cited by: 32
Author(s): Shuichi Machida, Satoshi Sekine, Yuka Nishiyama, Naoki Horikoshi, Hitoshi Kurumizaka
Software Mentions: 2
Published: about 10 years ago
10.1016/j.jsb.2015.08.009
Polyhedra structures and the evolution of the insect viruses
Cited by: 23
Author(s): Xiaoyun Ji, Danny Axford, Robin L. Owen, Gwyndaf Evans, H. Ginn, Geoff Sutton, David I. Stuart
Software Mentions: 2
Published: almost 11 years ago
10.18632/oncotarget.21652
Structural basis of the therapeutic anti-PD-L1 antibody atezolizumab
Cited by: 54
Author(s): Fei Zhang, Xiaoqiang Qi, Xiaoxiao Wang, Diyang Wei, Jiawei Wu, Lingling Feng, Haiyan Cai, Yugang Wang, Naiyan Zeng, Ting Xu, Aiwu Zhou, Ying Zheng
Software Mentions: 2
Published: almost 9 years ago
10.3390/ijms22136830
‘All That Glitters Is Not Gold’: High-Resolution Crystal Structures of Ligand-Protein Complexes Need Not Always Represent Confident Binding Poses
Cited by: 6
Author(s): Sohini Chakraborti, Kaushik Hatti, Narayanaswamy Srinivasan
Software Mentions: 2
Published: about 5 years ago
10.3390/ijms22179140
Structural and Functional Characterizations of Cancer Targeting Nanoparticles Based on Hepatitis B Virus Capsid
Cited by: 0
Author(s): Yunseok Heo, Hyomin Jeong, Youngki Yoo, Ji-Hye Yun, Bumhan Ryu, Young-je Cha, Boram Lee, Ye-Eun Jeon, Jongmin Kim, S.-H. Jeong, Eunji Jo, Jae Sung Woo, Jeewon Lee, Hyun-Soo Cho, Weontae Lee
Software Mentions: 2
Published: almost 5 years ago
10.1155/2017/4342789
Identification, Characterization, and Structure of Tm16 from<i>Trichuris muris</i>
Cited by: 10
Author(s): Zhuyun Liu, Alan Kelleher, Shanii Tabb, Junfei Wei, Jeroen Pollet, Peter J. Hotez, María Elena Bottazzi, Bin Zhan, Oluwatoyin A. Asojo
Software Mentions: 2
Published: over 9 years ago
10.3390/ijms21155277
Biophysical Characterization of Cancer-Related Carbonic Anhydrase IX
Cited by: 4
Author(s): Katarina Koruza, Akilah B. Murray, Brian P. Mahon, Jesse B. Hopkins, Wolfgang Knecht, Robert McKenna, S.Z. Fisher
Software Mentions: 2
Published: about 6 years ago
10.3390/ijms21072600
Structural Characterization of an ACP from Thermotoga maritima: Insights into Hyperthermal Adaptation
Cited by: 8
Author(s): Yeongjoon Lee, Ahjin Jang, Min‐Cheol Jeong, Nuri Park, Jungwoo Park, Woo Cheol Lee, Chaejoon Cheong, Yangmee Kim
Software Mentions: 2
Published: over 6 years ago
10.3390/ijms22063219
Crystal Structure of a Phospholipase D from the Plant-Associated Bacteria Serratia plymuthica Strain AS9 Reveals a Unique Arrangement of Catalytic Pocket
Cited by: 7
Author(s): Fanghua Wang, Siyu Liu, Xuejing Mao, Ruiguo Cui, Bo Yang, Yonghua Wang
Software Mentions: 2
Published: over 5 years ago
10.3390/ijms20061392
Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands
Cited by: 23
Author(s): Francisco de Asís Balaguer, Tobias Mühlethaler, Juan Estévez-Gallego, Enrique Calvo, Juan F. Giménez-Abián, April L. Risinger, Erik J. Sorensen, Christopher D. Vanderwal, Karl‐Heinz Altmann, Susan L. Mooberry, Michel O. Steinmetz, M.A. Oliva, A.E. Prota, J. Fernando Díaz
Software Mentions: 2
Published: over 7 years ago
10.15252/embj.2020106164
Cryo‐EM reveals the complex architecture of dynactin's shoulder region and pointed end
Cited by: 15
Author(s): C.K. Lau, Francis J. O’Reilly, S. Balaji, Samuel E Lacey, Juri Rappsilber, Andrew P. Carter
Software Mentions: 2
Published: over 5 years ago
10.7554/eLife.57887
The architecture of EMC reveals a path for membrane protein insertion
Cited by: 72
Author(s): John P. O’Donnell, Ben P. Phillips, Yuichi Yagita, Szymon Juszkiewicz, Armin Wagner, Duccio Malinverni, Robert J. Keenan, Elizabeth A. Miller, Ramanujan S. Hegde
Software Mentions: 2
Published: about 6 years ago
10.3390/ijms20071533
The Molecular and Structural Basis of O-methylation Reaction in Coumarin Biosynthesis in Peucedanum praeruptorum Dunn
Cited by: 13
Author(s): Yucheng Zhao, Nana Wang, Ziwei Sui, C.H. Huang, Zhixiong Zeng, Ling‐Yi Kong
Software Mentions: 2
Published: over 7 years ago
10.1016/j.jsb.2014.12.002
Seeing tobacco mosaic virus through direct electron detectors
Cited by: 82
Author(s): Simon A. Fromm, Tanmay A. M. Bharat, Arjen J. Jakobi, Wim J. H. Hagen, Carsten Sachse
Software Mentions: 2
Published: over 11 years ago
10.7554/eLife.60482
Structure of the bacterial ribosome at 2 Å resolution
Cited by: 125
Author(s): Zoe L Watson, Fred R. Ward, Raphaël Méheust, Omer Ad, Alanna Schepartz, Jillian F. Banfield, Jamie H. D. Cate
Software Mentions: 2
Published: almost 6 years ago
10.7554/eLife.02375
AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter
Cited by: 44
Author(s): Ursula Schulze‐Gahmen, Huasong Lu, Qiang Zhou, Tom Alber
Software Mentions: 2
Published: over 12 years ago
10.7554/eLife.42400
DNA translocation mechanism of an XPD family helicase
Cited by: 32
Author(s): Kaiying Cheng, Dale B. Wigley
Software Mentions: 2
Published: over 7 years ago
10.7554/eLife.33442
Decoding the centromeric nucleosome through CENP-N
Cited by: 98
Author(s): Satyakrishna Pentakota, Keda Zhou, Charlotte M. Smith, Stefano Maffini, Arsen Petrovic, Garry Morgan, John R. Weir, Ingrid R. Vetter, Andrea Musacchio, Karolin Luger
Software Mentions: 2
Published: over 8 years ago
10.7554/eLife.51492
Structural basis of substrate recognition by a polypeptide processing and secretion transporter
Cited by: 23
Author(s): Virapat Kieuvongngam, Paul Dominic B. Olinares, Anthony Palillo, Michael L. Oldham, Brian T. Chait, Jue Chen
Software Mentions: 2
Published: over 6 years ago
10.7554/eLife.06074
Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate
Cited by: 74
Author(s): Qi Wang, Erik Vogan, Laura M. Nocka, Connor Rosen, Julie A. Zorn, Stephen C. Harrison, John Kuriyan
Software Mentions: 2
Published: over 11 years ago
10.7554/eLife.03579
Structure and substrate ion binding in the sodium/proton antiporter PaNhaP
Cited by: 82
Author(s): David Wöhlert, Werner Kühlbrandt, Özkan Yıldız
Software Mentions: 2
Published: over 11 years ago
10.7554/eLife.32893
IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
Cited by: 39
Author(s): Yoshimasa Yoneyama, Peter Lanzerstorfer, Hideaki Niwa, Takashi Umehara, Takashi Shibano, Shigeyuki Yokoyama, Kazuhiro Chida, Julian Weghuber, Fumihiko Hakuno, Shinichiro Takahashi
Software Mentions: 2
Published: over 8 years ago
10.7554/eLife.42150
Structural organization of a major neuronal G protein regulator, the RGS7-Gβ5-R7BP complex
Cited by: 17
Author(s): Dipak N. Patil, Erumbi S. Rangarajan, Scott J. Novick, Bruce D. Pascal, D.J. Kojetin, Patrick R. Griffin, Tina Izard, Kirill A. Martemyanov
Software Mentions: 2
Published: over 7 years ago
10.7554/eLife.68710
Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation
Cited by: 34
Author(s): P. Kolata, Rouslan G. Efremov
Software Mentions: 2
Published: about 5 years ago
10.7554/eLife.17983
Structures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia
Cited by: 53
Author(s): F. Esra Demircioglu, Brian A Sosa, Jessica R. Ingram, Hidde L. Ploegh, Thomas Schwartz
Software Mentions: 2
Published: about 10 years ago
10.1016/j.jbc.2021.100321
Structural characterization of HIV-1 matrix mutants implicated in envelope incorporation
Cited by: 5
Author(s): Gunnar N. Eastep, Ruba H. Ghanam, Todd Green, Jamil S. Saad
Software Mentions: 2
Published: over 5 years ago
10.1038/s42003-021-02068-3
Identification of a peptide motif that potently inhibits two functionally distinct subunits of Shiga toxin
Cited by: 5
Author(s): Miho Watanabe-Takahashi, Masakazu Tamada, Masuo Senda, M. Hibino, Eihan Shimizu, Akiko Okuta, Atsuo Miyazawa, Toshiya Senda, Kiyotaka Nishikawa
Software Mentions: 2
Published: over 5 years ago
10.7554/eLife.00184
Distinct gating mechanisms revealed by the structures of a multi-ligand gated K+ channel
Cited by: 22
Author(s): Chunguang Kong, Weizhong Zeng, Sheng Ye, Liping Chen, David Sauer, Y. Amy Lam, M.G. Derebe, Youxing Jiang
Software Mentions: 2
Published: over 13 years ago
10.7554/eLife.21510
Structural insights into the mechanism of the DEAH-box RNA helicase Prp43
Cited by: 75
Author(s): M.J. Tauchert, Jean‐Baptiste Fourmann, Reinhard Lührmann, Ralf Ficner
Software Mentions: 2
Published: over 9 years ago
10.1016/j.jsb.2016.08.006
Structures of type IV pilins from Thermus thermophilus demonstrate similarities with type II secretion system pseudopilins
Cited by: 11
Author(s): V. Karuppiah, Angela Thistlethwaite, Jeremy P. Derrick
Software Mentions: 2
Published: over 9 years ago
10.7554/eLife.56451
Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses
Cited by: 47
Author(s): Ling Wang, Z.L. Johnson, Mark Wasserman, Jesper Levring, Jue Chen, Shixin Liu
Software Mentions: 2
Published: about 6 years ago
10.7554/eLife.31502
3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound
Cited by: 34
Author(s): Edward J. Brignole, Kuang‐Lei Tsai, Johnathan Chittuluru, Haoran Li, Yimon Aye, Pawel A. Penczek, Jo Anne Stubbe, Catherine L. Drennan, Francisco J. Asturias
Software Mentions: 2
Published: over 8 years ago
10.7554/eLife.21600
Crenactin forms actin-like double helical filaments regulated by arcadin-2
Cited by: 31
Author(s): Thierry Izoré, Danguole Kureisaite-Ciziene, Stephen H. McLaughlin, Jan Löwe
Software Mentions: 2
Published: over 9 years ago
10.7554/eLife.36340
Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-d]pyrimidine non-nucleoside inhibitors
Cited by: 53
Author(s): Yang Yang, Dongwei Kang, Laura A. Nguyen, Z.B. Smithline, Christophe Pannecouque, Peng Zhan, Xinyong Liu, Thomas A. Steitz
Software Mentions: 2
Published: about 8 years ago
10.7554/eLife.06792
Acidic pH and divalent cation sensing by PhoQ are dispensable for systemic salmonellae virulence
Cited by: 26
Author(s): Kevin G. Hicks, Scott P. Delbecq, Enea Sancho‐Vaello, Marie-Pierre Blanc, Katja K. Dove, Lynne R. Prost, Margaret E. Daley, Kornelius Zeth, Rachel E. Klevit, Samuel I. Miller
Software Mentions: 2
Published: about 11 years ago
10.7554/eLife.00482
Mechanism for priming DNA synthesis by yeast DNA Polymerase α
Cited by: 89
Author(s): Rajika L. Perera, Rubben Torella, Sebastian Klinge, M.L. Kilkenny, Joseph D. Maman, Luca Pellegrini
Software Mentions: 2
Published: over 13 years ago
10.7554/eLife.07574
Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography
Cited by: 140
Author(s): D.A. Keedy, Lukas Kenner, Matthew Warkentin, R.A. Woldeyes, Jesse B. Hopkins, Michael C. Thompson, Aaron S. Brewster, A.H. Van Benschoten, E.L. Baxter, Monarin Uervirojnangkoorn, S.E. McPhillips, Jianguo Song, Roberto Alonso-Mori, James M. Holton, William I. Weis, Axel T. Brunger, S. Michael Soltis, Henrik T. Lemke, Ana González, Nicholas K. Sauter, Aina E. Cohen, Henry van den Bedem, Robert Thorne, James S. Fraser
Software Mentions: 2
Published: almost 11 years ago
10.7554/eLife.44353
Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint
Cited by: 33
Author(s): Nicolas Bigot, Matthew Day, Robert A. Baldock, Felicity Z. Watts, Antony W. Oliver, Laurence H. Pearl
Software Mentions: 2
Published: about 7 years ago
10.15252/embj.2020105908
Structure and elevator mechanism of the mammalian sodium/proton exchanger NHE9
Cited by: 27
Author(s): Iven Winkelmann, Ryota Matsuoka, Pascal Meier, Denis Shutin, Chen‐Ou Zhang, Laura Orellana, Ricky Sexton, Michael Landreh, Carol V. Robinson, Oliver Beckstein, David Drew
Software Mentions: 2
Published: almost 6 years ago
10.7554/eLife.51511
Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 receptor via a common vestibule site
Cited by: 13
Author(s): Marijke Brams, Cédric Govaerts, Kumiko Kambara, Kerry L. Price, Radovan Spurný, Anant Gharpure, Els Pardon, G.L. Evans, Daniel Bertrand, Sarah S.C.R. Lummis, Ryan Hibbs, Jan Steyaert, Chris Ulens
Software Mentions: 2
Published: over 6 years ago
10.7554/eLife.62518
Structure of bacterial phospholipid transporter MlaFEDB with substrate bound
Cited by: 42
Author(s): Nicolas Coudray, Georgia L. Isom, M.R. MacRae, Mariyah N. Saiduddin, Gira Bhabha, D.C. Ekiert
Software Mentions: 2
Published: over 5 years ago
10.1038/s41422-020-0319-4
Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex by cryo-electron microscopy single particle analysis
Cited by: 48
Author(s): Guangli Huang, Yanqing Zhang, Xinhui Zhu, Chao Zeng, Qifan Wang, Qiang Zhou, Qinghua Tao, Minhao Liu, Jianlin Lei, Chuangye Yan, Yigong Shi
Software Mentions: 2
Published: over 6 years ago
10.1038/s42003-020-01147-1
Molecular basis of the lipid-induced MucA-MucB dissociation in Pseudomonas aeruginosa
Cited by: 6
Author(s): Tao Li, Libang He, Changcheng Li, Mei Kang, Yingjie Song, Yuanfeng Zhu, Yanjiao Shen, Ninglin Zhao, Chang Zhao, Jing Yang, Qin Huang, Xingyu Mou, Aiping Tong, Jinliang Yang, Zhenling Wang, Chengjie Ji, Hong Li, Hong Tang, Rui Bao
Software Mentions: 2
Published: about 6 years ago
10.15252/embj.2018101414
Coupling of ATPase activity, microtubule binding, and mechanics in the dynein motor domain
Cited by: 19
Author(s): Stefan Niekamp, Nicolas Coudray, Nan Zhang, Ronald D. Vale, Gira Bhabha
Software Mentions: 2
Published: about 7 years ago
10.1038/s42003-021-02326-4
Structure-based insights into evolution of rhodopsins
Cited by: 13
Author(s): Dmitrii Zabelskii, Natalia I. Dmitrieva, Oleksandr Volkov, Vitaly Shevchenko, Kirill Kovalev, Taras Balandin, Dmytro Soloviov, Roman Astashkin, Egor V. Zinovev, Alexey Alekseev, Ekaterina Round, Vitaly Polovinkin, Igor Chizhov, Andrey Rogachev, Ivan Okhrimenko, Valentin Borshchevskiy, Vladimir Chupin, Georg Büldt, Natalia Yutin, Ernst Bamberg, Eugene V. Koonin, Valentin Gordeliy
Software Mentions: 2
Published: about 5 years ago
10.7554/eLife.52774
Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate
Cited by: 94
Author(s): Fei X, Tristan A Bell, Simon Jenni, Benjamin M. Stinson, T.A. Baker, Stephen C. Harrison, Robert T. Sauer
Software Mentions: 2
Published: over 6 years ago
10.7554/eLife.43229
Structural basis of Ca2+-dependent activation and lipid transport by a TMEM16 scramblase
Cited by: 81
Author(s): Maria Falzone, Jan Rheinberger, B.C. Lee, Thasin Peyear, Linda Sasset, Ashleigh M. Raczkowski, Edward T. Eng, Annarita Di Lorenzo, Olaf S. Andersen, Crina M. Nimigean, Alessio Accardi
Software Mentions: 2
Published: over 7 years ago
10.7554/eLife.22679
Evolution of substrate specificity in a retained enzyme driven by gene loss
Cited by: 21
Author(s): Ana Lilia Juárez-Vázquez, Janaka N. Edirisinghe, E.A. Verduzco-Castro, K. Michalska, Chenggang Wu, Lianet Noda-García, G. Babnigg, M. Endres, Sofía Medina-Ruiz, Julián Santoyo-Flores, Mauricio Carrillo‐Tripp, Hung Ton‐That, A. Joachimiak, Christopher S. Henry, Francisco Barona‐Gómez
Software Mentions: 2
Published: over 9 years ago
10.1080/14756366.2020.1837123
Crystal structure-guided design of berberine-based novel chitinase inhibitors
Cited by: 13
Author(s): Lei Chen, Ling Zhu, Jinli Chen, Wei Chen, Xuhong Qian, Qing Yang
Software Mentions: 2
Published: over 6 years ago
10.7554/eLife.28020
A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency
Cited by: 39
Author(s): Manabu Aoki, Hironori Hayashi, Kalapala Venkateswara Rao, Debananda Das, Nobuyo Higashi-Kuwata, Haydar Bulut, Hiromi Aoki-Ogata, Yuki Takamatsu, Ravikiran S. Yedidi, David A. Davis, Shin Hattori, Noriko Nishida, Kazuya Hasegawa, Nobutoki Takamune, Prasanth R. Nyalapatla, Heather L. Osswald, Hirofumi Jono, Hideyuki Saya, Robert Yarchoan, Shogo Misumi, Arun K. Ghosh, Hiroaki Mitsuya
Software Mentions: 2
Published: almost 9 years ago
10.3390/ijms17040446
Structure of the PLP-Form of the Human Kynurenine Aminotransferase II in a Novel Spacegroup at 1.83 Å Resolution
Cited by: 13
Author(s): Alireza Nematollahi, Guorong Sun, S.J. Harrop, Jane R. Hanrahan, W. Bret Church
Software Mentions: 2
Published: over 10 years ago
10.3390/ijms18071336
Quinolin-6-Yloxyacetamides Are Microtubule Destabilizing Agents That Bind to the Colchicine Site of Tubulin
Cited by: 9
Author(s): Ashwani Sharma, Gonzalo Sáez-Calvo, Natacha Olieric, Francisco de Asís Balaguer, Isabel Barasoaín, Clemens Lamberth, J. Fernando Díaz, Michel O. Steinmetz
Software Mentions: 2
Published: about 9 years ago
10.3390/ijms20246279
Structural Insights into the Intracellular Region of the Human Magnesium Transport Mediator CNNM4
Cited by: 13
Author(s): Paula Giménez-Mascarell, Iker Oyenarte, Irene González‐Recio, Carmen Fernández‐Rodríguez, María Ángeles Corral-Rodríguez, Igone Campos-Zarraga, Jorge Simón, Elie Kostantin, Serge Hardy, Antonio Díaz-Quintana, Mara Zubillaga Lizeaga, Nekane Merino, Tammo Diercks, Francisco J. Blanco, Irene Dίaz–Moreno, María Luz Martínez‐Chantar, Michel L. Tremblay, Dominik Müller, Dritan Siliqi, Luis Alfonso Martínez-Cruz
Software Mentions: 2
Published: over 6 years ago
10.3390/ijms21010083
The Structure of Sucrose-Soaked Levansucrase Crystals from Erwinia tasmaniensis reveals a Binding Pocket for Levanbiose
Cited by: 14
Author(s): Ivan Polsinelli, Rosanna Caliandro, Nicola Demitri, Stefano Benini
Software Mentions: 2
Published: over 6 years ago
10.15252/embr.201745680
Active site alanine mutations convert deubiquitinases into high‐affinity ubiquitin‐binding proteins
Cited by: 40
Author(s): Marie E. Morrow, Michael T. Morgan, Marcello Clerici, Kateřina Growková, Ming Yan, David Komander, Titia K. Sixma, Michal Šimíček, Cynthia Wolberger
Software Mentions: 2
Published: almost 8 years ago
10.3390/ijms21197081
Impact of HLA-DR Antigen Binding Cleft Rigidity on T Cell Recognition
Cited by: 5
Author(s): Christopher Szeto, Joseph Bloom, Hannah Sloane, Christian A. Lobos, James Fodor, Dhilshan Jayasinghe, D.S.M. Chatzileontiadou, Emma J. Grant, Ashley M. Buckle, Stéphanie Gras
Software Mentions: 2
Published: almost 6 years ago
10.1002/cbic.201800462
Structure and Catalytic Mechanism of a Bacterial Friedel–Crafts Acylase
Cited by: 23
Author(s): Tea Pavkov‐Keller, Nina G. Schmidt, Anna Żądło‐Dobrowolska, Wolfgang Kroutil, Karl Gruber
Software Mentions: 2
Published: over 7 years ago
10.3390/ijms22136859
Sub-3 Å Cryo-EM Structures of Necrosis Virus Particles via the Use of Multipurpose TEM with Electron Counting Camera
Cited by: 1
Author(s): Chun-Hsiung Wang, Donghua Chen, Shih-Hsin Huang, Yimin A. Wu, Yiyun Chen, Y. Hwu, David Bushnell, Roger D. Kornberg, Wen Ho Chang
Software Mentions: 2
Published: about 5 years ago
10.3390/ijms221910862
Loops around the Heme Pocket Have a Critical Role in the Function and Stability of BsDyP from Bacillus subtilis
Cited by: 7
Author(s): Carolina Rodrigues, Patrícia T. Borges, Magalí F. Scocozza, Diogo Silva, André Taborda, Vânia Brissos, Carlos Frazão, Lı́gia O. Martins
Software Mentions: 2
Published: almost 5 years ago