Projects: cran: PHENIX

https://packages.ecosyste.ms/registries/cran.r-project.org/packages/PHENIX

Phenotypic Integration Index
7 versions
Latest release: over 9 years ago
1 dependent package
161 downloads last month

Science Score: 75/100
Starting Score: 100 points
Penalties:
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Very Likely Science (75)

Papers Mentioning PHENIX 2,287

10.1186/s13072-016-0051-y
Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis
Cited by: 51
Author(s): Takashi Urahama, Akihito Harada, Kazuhira Maehara, Naoki Horikoshi, Koichi Sato, Yuko Sato, Koji Shiraishi, Norihiro Sugino, Akihisa Osakabe, Hiroaki Tachiwana, Wataru Kagawa, Hiroshi Kimurâ, Yasuyuki Ohkawa, Hitoshi Kurumizaka
Software Mentions: 3
Published: almost 11 years ago
10.1038/s42003-021-02532-0
Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn2+ ions
Cited by: 7
Author(s): Владислав А. Лушпа, Marina V. Goncharuk, Cong Lin, Arthur O. Zalevsky, Irina A. Talyzina, Aleksandra Luginina, Daniil Vakhrameev, M.B. Shevtsov, Sergey A. Goncharuk, Alexander S. Arseniev, Valentin Borshchevskiy, Xiaohui Wang, K.S. Mineev
Software Mentions: 3
Published: about 5 years ago
10.1038/s41598-019-40432-w
Reactive centre loop dynamics and serpin specificity
Cited by: 28
Author(s): Emilia M. Marijanovic, James Fodor, Blake T. Riley, Benjamin T. Porebski, Maurício G. S. Costa, Itamar Kass, David E. Hoke, Sheena McGowan, Ashley M. Buckle
Software Mentions: 3
Published: over 7 years ago
10.15252/embj.2021107985
Neutralization of SARS‐CoV‐2 by highly potent, hyperthermostable, and mutation‐tolerant nanobodies
Cited by: 56
Author(s): Thomas Güttler, Metin Aksu, Antje Dickmanns, Kim M. Stegmann, Kathrin Gregor, Renate Rees, Waltraud Taxer, Oleh Rymarenko, Jürgen Schünemann, Christian Dienemann, Philip Gunkel, Bianka Mußil, Jens Krull, Ulrike Teichmann, Uwe Groß, Volker C. Cordes, Matthias Dobbelstein, Dirk Görlich
Software Mentions: 3
Published: about 5 years ago
10.1038/s41598-019-39588-2
The IKK-binding domain of NEMO is an irregular coiled coil with a dynamic binding interface
Cited by: 18
Author(s): Adam H. Barczewski, Michael J. Ragusa, Dale F. Mierke, Maria Pellegrini
Software Mentions: 3
Published: over 7 years ago
10.1038/s42003-021-02518-y
14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites
Cited by: 18
Author(s): Matej Horvath, Olívia Petrvalská, Petr Heřman, Veronika Obšilová, Tomáš Obšil
Software Mentions: 3
Published: about 5 years ago
10.15252/embj.2018100825
Diverse roles of TssA‐like proteins in the assembly of bacterial type VI secretion systems
Cited by: 34
Author(s): Johannes Schneider, Sergey Nazarov, Ricardo Adaixo, Martina Liuzzo, Peter David Ringel, Henning Stahlberg, Marek Basler
Software Mentions: 3
Published: about 7 years ago
10.1038/s41598-019-39641-0
Structural basis of small RNA hydrolysis by oligoribonuclease (CpsORN) from Colwellia psychrerythraea strain 34H
Cited by: 13
Author(s): Chang Woo Lee, Sun Ha Park, Chang-Sung Jeong, Sun Mi Shin, Hyun Park, Jun Hyuck Lee
Software Mentions: 3
Published: over 7 years ago
10.7554/eLife.60552
Cryo-EM analysis of PIP2 regulation in mammalian GIRK channels
Cited by: 43
Author(s): Yiming Niu, Xiao Tao, Kouki K Touhara, Roderick MacKinnon
Software Mentions: 3
Published: about 6 years ago
10.1038/s41598-018-37522-6
MITF has a central role in regulating starvation-induced autophagy in melanoma
Cited by: 60
Author(s): Katrín Möller, Sara Sigurbjörnsdóttir, Asgeir Ö. Arnthórsson, Vivian Pogenberg, Ramile Dilshat, Valerie Fock, Sólveig Hlín Brynjólfsdóttir, Christian Bindesbøll, M. Bessadóttir, Helga M. Ögmundsdóttir, Anne Simonsen, Lionel Larue, Matthias Wilmanns, Vésteinn Thórsson, Eiríkur Steingrimsson, Margrét H. Ögmundsdóttir
Software Mentions: 3
Published: over 7 years ago
10.1111/cea.12230
Human <scp>I</scp> g <scp>E</scp> against the major allergen <scp>B</scp> et v 1 – defining an epitope with limited cross‐reactivity between different <scp>PR</scp> ‐10 family proteins
Cited by: 20
Author(s): Mattias Levin, Anna M. Davies, Maria Liljekvist, Fredrika Carlsson, Hannah J. Gould, Brian J. Sutton, Mats Ohlin
Software Mentions: 3
Published: almost 13 years ago
10.1038/s41598-018-33193-5
Structural insights into the electron/proton transfer pathways in the quinol:fumarate reductase from Desulfovibrio gigas
Cited by: 10
Author(s): Hong‐Hsiang Guan, Yin-Cheng Hsieh, Po‐Chun Lin, Yen‐Chieh Huang, Masato Yoshimura, Liying Chen, Shao-Kang Chen, Phimonphan Chuankhayan, Chien-Chih Lin, Nai-Chi Chen, Atsushi Nakagawa, Sunney I. Chan, Chun‐Jung Chen
Software Mentions: 3
Published: about 8 years ago
10.7554/eLife.59225
Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers
Cited by: 33
Author(s): William Wan, Mairi Clarke, Michael Norris, Larissa Kolesnikova, Alexander Koehler, Zachary A. Bornholdt, Stephan Becker, Erica Ollmann Saphire, John Briggs
Software Mentions: 3
Published: about 6 years ago
10.1038/s41598-018-30154-w
Genome-wide association study and genomic prediction using parental and breeding populations of Japanese pear (Pyrus pyrifolia Nakai)
Cited by: 44
Author(s): Mai F. Minamikawa, Norio Takada, Shingo Terakami, Toshihiro Saito, Akio Onogi, Hiromi Kajiya‐Kanegae, Takeshi Hayashi, Takatsugu Yamamoto, Hiroyoshi Iwata
Software Mentions: 3
Published: about 8 years ago
10.1038/s41598-018-29664-4
Structural basis for selective inhibition of immunoglobulin E-receptor interactions by an anti-IgE antibody
Cited by: 20
Author(s): Jiun-Bo Chen, Faruk Ramadani, M.O.Y. Pang, Rebecca L. Beavil, Mary D. Holdom, A.N. Mitropoulou, Andrew J. Beavil, Hannah J. Gould, Tse Wen Chang, Brian J. Sutton, James M. McDonnell, Anna M. Davies
Software Mentions: 3
Published: about 8 years ago
10.1038/s41422-018-0104-9
Plant HP1 protein ADCP1 links multivalent H3K9 methylation readout to heterochromatin formation
Cited by: 71
Author(s): Shuai Zhao, Lan Cheng, Yifei Gao, Baichao Zhang, Xiangdong Zheng, Liang Wang, Pilong Li, Qianwen Sun, Haitao Li
Software Mentions: 3
Published: almost 8 years ago
10.1038/s42003-020-01123-9
Structure and function of a malaria transmission blocking vaccine targeting Pfs230 and Pfs230-Pfs48/45 proteins
Cited by: 34
Author(s): Kavita Singh, Martin Burkhardt, Sofia Nakuchima, Raúl Herrera, Olga Muratova, Apostolos G. Gittis, Emily Kelnhofer, Karine Reiter, Margery Smelkinson, Daniel Veltri, Bruce J. Swihart, Richard L. Shimp, Vu Nguyen, Baoshan Zhang, Nicholas J. MacDonald, Patrick E. Duffy, David N. Garboczi, David L. Narum
Software Mentions: 3
Published: over 6 years ago
10.1038/s41598-018-29058-6
Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin
Cited by: 7
Author(s): Mekdes Debela, Viktor Magdolen, Wolfgang Skala, Brigitta Elsässer, Eric L. Schneider, Charles S. Craik, Martin L. Biniossek, Oliver Schilling, Wolfram Bode, Hans Brandstetter, Peter Goettig
Software Mentions: 3
Published: over 8 years ago
10.1016/j.jmb.2015.08.023
Atomic-Resolution Structures of the APC/C Subunits Apc4 and the Apc5 N-Terminal Domain
Cited by: 9
Author(s): Nora Cronin, Jing Yang, Ziguo Zhang, Kiran Kulkarni, Leifu Chang, Hiroyuki Yamano, David Barford
Software Mentions: 3
Published: about 11 years ago
10.7554/eLife.17903
A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading
Cited by: 32
Author(s): Chun-Min Shan, Jiyong Wang, Ke Xu, Huijie Chen, Jia-Xing Yue, Stuart Andrews, James J. Moresco, John R. Yates, Péter L. Nagy, Liang Tong, Songtao Jia
Software Mentions: 3
Published: about 10 years ago
10.1016/j.jmb.2015.10.027
A Substrate Mimic Allows High-Throughput Assay of the FabA Protein and Consequently the Identification of a Novel Inhibitor of Pseudomonas aeruginosa FabA
Cited by: 6
Author(s): L. Moynié, Anthony G. Hope, Kara Finzel, J.W. Schmidberger, Stuart M. Leckie, Günter Schneider, Michael D. Burkart, Andrew D. Smith, David W. Gray, James H. Naismith
Software Mentions: 3
Published: almost 11 years ago
10.1038/s41598-018-26601-3
Molecular recognition of wood polyphenols by phase II detoxification enzymes of the white rot Trametes versicolor
Cited by: 36
Author(s): Mathieu Schwartz, Thomas Perrot, Emmanuel Aubert, Stéphane Dumarçay, F. Favier, Philippe Gérardin, Mélanie Morel‐Rouhier, Guillermo Mulliert, Fanny Saiag, Claude Didierjean, Éric Gelhaye
Software Mentions: 3
Published: over 8 years ago
10.1371/journal.ppat.1003754
The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies
Cited by: 165
Author(s): Devin Sok, Uri Laserson, Jonathan Laserson, Yiping Liu, François Vigneault, Jean-Philippe Julien, Bryan Briney, Alejandra Ramos, Karen Saye, Khoa Le, Alison E. Mahan, Shenshen Wang, Mehran Kardar, Gur Yaari, Laura M. Walker, Birgitte B. Simen, Elizabeth St. John, Po-Ying Chan-Hui, Kristine M. Swiderek, Stephen H. Kleinstein, Galit Alter, Michael S. Seaman, Arup K. Chakraborty, Daphne Koller, Ian A. Wilson, George M. Church, Dennis R. Burton, Pascal Poignard
Software Mentions: 3
Published: almost 13 years ago
10.1371/journal.ppat.1002957
De novo GTP Biosynthesis Is Critical for Virulence of the Fungal Pathogen Cryptococcus neoformans
Cited by: 53
Author(s): Carl A. Morrow, Eugene Valkov, Anna Stamp, Eve W. L. Chow, I. Russel Lee, Ania Wronski, Simon J. Williams, Jennifer Hill, Julianne T. Djordjevic, Ulrike Kappler, Boštjan Kobe, James S. Fraser
Software Mentions: 3
Published: about 14 years ago
10.1080/14756366.2021.1931862
Structure-based virtual screening of highly potent inhibitors of the nematode chitinase <i>Ce</i>Cht1
Cited by: 7
Author(s): Wei Chen, Qi Chen, Ashutosh Kumar, Xi Jiang, Kam Y. J. Zhang, Qing Yang
Software Mentions: 3
Published: almost 6 years ago
10.1016/j.jmb.2013.10.039
Structural Determinants of Unique Properties of Human IgG4-Fc
Cited by: 95
Author(s): Anna M. Davies, Theo Rispens, Pleuni Ooijevaar-de Heer, Hannah J. Gould, Royston Jefferis, Rob C. Aalberse, Brian J. Sutton
Software Mentions: 3
Published: over 12 years ago
10.1186/s13045-020-00979-y
Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma
Cited by: 28
Author(s): Kecheng Lei, Xiaoxia Gu, Alvaro G. Alvarado, Yuhong Du, Shilin Luo, Eun Hee Ahn, Seong Su Kang, Bing Ji, Xia Liu, Hui Mao, Haian Fu, Harley I. Kornblum, Lingjing Jin, Li Hua, Keqiang Ye
Software Mentions: 3
Published: about 6 years ago
10.1016/j.jbc.2021.101061
A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase
Cited by: 7
Author(s): Emily Chen, Krystle Reiss, Dilip Shah, R Manjula, Brandon Allen, Eva Murphy, James W. Murphy, Víctor S. Batista, Vineet Bhandari, Elias Lolis, George P. Lisi
Software Mentions: 3
Published: about 5 years ago
10.1016/j.jbc.2021.100927
Beyond PKA: Evolutionary and structural insights that define a docking and dimerization domain superfamily
Cited by: 3
Author(s): Heather R. Dahlin, Ning Zheng, John D. Scott
Software Mentions: 3
Published: about 5 years ago
10.1016/j.jbc.2021.100743
From integrative structural biology to cell biology
Cited by: 38
Author(s): Andrej Šali
Software Mentions: 3
Published: almost 6 years ago
10.1016/j.jbc.2021.100700
ZapG (YhcB/DUF1043), a novel cell division protein in gamma-proteobacteria linking the Z-ring to septal peptidoglycan synthesis
Cited by: 8
Author(s): Jitender Mehla, George W. Liechti, Randy M. Morgenstein, J. Harry Caufield, Ali Hosseinnia, Alla Gagarinova, Sadhna Phanse, Norman Goodacre, Mary R. Brockett, Neha Sakhawalkar, Mohan Babu, Rong Xiao, Gaetano T. Montelione, S.M. Vorobiev, T. den Blaauwen, J.F. Hunt, Peter Uetz
Software Mentions: 3
Published: almost 6 years ago
10.1074/jbc.RA120.012788
Small molecule AX-024 reduces T cell proliferation independently of CD3ϵ/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain
Cited by: 10
Author(s): Kirsten Richter, Arne C. Rufer, Magali Muller, Dominique Burger, Fabio Casagrande, Tabea Grossenbacher, Sylwia Huber, Melanie N. Hug, Philipp Koldewey, Andrea D’Osualdo, Daniel Schlatter, Theodor Stoll, M.G. Rudolph
Software Mentions: 3
Published: over 6 years ago
10.1074/jbc.RA119.010697
Structural basis of cell-surface signaling by a conserved sigma regulator in Gram-negative bacteria
Cited by: 3
Author(s): Jaime L. Jensen, Beau D. Jernberg, Sangita C. Sinha, Christopher L. Colbert
Software Mentions: 3
Published: over 6 years ago
10.1074/jbc.RA119.007709
Structure and interactions of the archaeal motility repression module ArnA–ArnB that modulates archaellum gene expression in Sulfolobus acidocaldarius
Cited by: 15
Author(s): Lena Hoffmann, Katrin Anders, Lisa Franziska Bischof, Xing Ye, Julia Reimann, Sunia Khadouma, Trong Khoa Pham, Chris van der Does, Phillip C. Wright, Lars‐Oliver Essen, Sonja‐Verena Albers
Software Mentions: 3
Published: over 7 years ago
10.1016/j.str.2013.10.013
Structure and Self-Assembly of the Calcium Binding Matrix Protein of Human Metapneumovirus
Cited by: 45
Author(s): C. Leyrat, Max Renner, K. Harlos, Juha T. Huiskonen, Jonathan M. Grimes
Software Mentions: 3
Published: almost 13 years ago
10.1074/jbc.RA118.006045
Structural insights into non-covalent ubiquitin activation of the cIAP1-UbcH5B∼ubiquitin complex
Cited by: 12
Author(s): Amrita Patel, Gary Sibbet, Danny T. Huang
Software Mentions: 3
Published: almost 8 years ago
10.1074/jbc.RA118.004469
Discovery of peptide ligands targeting a specific ubiquitin-like domain–binding site in the deubiquitinase USP11
Cited by: 24
Author(s): Anastasios Spiliotopoulos, Lia Blokpoel Ferreras, Ruth M Densham, Simon G. Caulton, Ben C. Maddison, Joanna R. Morris, James E. Dixon, Kevin C. Gough, Ingrid Dreveny
Software Mentions: 3
Published: almost 8 years ago
10.1074/jbc.M117.806893
Negatively charged residues in the first extracellular loop of the L-type CaV1.2 channel anchor the interaction with the CaVα2δ1 auxiliary subunit
Cited by: 16
Author(s): Benoîte Bourdin, Julie Briot, Marie-Philippe Tétreault, Rémy Sauvé, Lucie Parent
Software Mentions: 3
Published: about 9 years ago
10.1063/4.0000087
Reproducibility of protein x-ray diffuse scattering and potential utility for modeling atomic displacement parameters
Cited by: 4
Author(s): Zhen Su, M. Dasgupta, Frédéric Poitevin, I.I. Mathews, H. van den Bedem, Michael E. Wall, Chun Hong Yoon, Mark A. Wilson
Software Mentions: 3
Published: over 5 years ago
10.1074/jbc.M117.776476
Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab
Cited by: 57
Author(s): Anna M. Davies, Elizabeth G. Allan, Anthony H. Keeble, Jean Delgado, Benjamin P. Cossins, A.N. Mitropoulou, M.O.Y. Pang, Tom Ceska, Andrew J. Beavil, Graham Craggs, Marta Westwood, Alistair J. Henry, James M. McDonnell, Brian J. Sutton
Software Mentions: 3
Published: over 9 years ago
10.7554/eLife.33274
Structural basis of proton translocation and force generation in mitochondrial ATP synthase
Cited by: 56
Author(s): N. Klusch, Bonnie J. Murphy, Deryck J. Mills, Özkan Yıldız, Werner Kühlbrandt
Software Mentions: 2
Published: almost 9 years ago
10.1038/s41422-020-0363-0
CryoEM structure of the tegumented capsid of Epstein-Barr virus
Cited by: 17
Author(s): Zhihai Li, Xiao Zhang, Lili Dong, Jingjing Pang, Miao Xu, Qian Zhong, Mu‐Sheng Zeng, Xuekui Yu
Software Mentions: 2
Published: over 6 years ago
10.1038/s41422-021-00514-9
Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines
Cited by: 109
Author(s): Yunlong Cao, Ayijiang Yisimayi, Yali Bai, Weijin Huang, Xiaofeng Li, Zhiying Zhang, Tianjiao Yuan, Ran An, Jing Wang, Tianhe Xiao, Shuo Du, Wenping Ma, Liyang Song, Yongzheng Li, Xiang Li, Weiliang Song, Jiajing Wu, Shuo Liu, Xuemei Li, Yonghong Zhang, Bin Su, Xuesong Guo, Yu‐Sheng Wei, Chuanping Gao, Nana Zhang, Yifei Zhang, Yang Dou, Xiaoyu Xu, Rui Shi, Lan Bai, Ronghua Jin, Yingmin Ma, Cheng‐Feng Qin, Youchun Wang, Yingmei Feng, Junyu Xiao, X. Sunney Xie
Software Mentions: 2
Published: over 5 years ago
10.1038/s41422-021-00474-0
Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca2+ ions and L-tryptophan
Cited by: 39
Author(s): Shenglong Ling, Peng Shi, Sanling Liu, Xianyu Meng, Ying Zhou, Wenjing Sun, Shenghai Chang, Xing Zhang, Longhua Zhang, Chaowei Shi, Degang Sun, Lei Liu, Changlin Tian
Software Mentions: 2
Published: over 5 years ago
10.1038/s41422-020-0319-4
Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex by cryo-electron microscopy single particle analysis
Cited by: 48
Author(s): Guangli Huang, Yanqing Zhang, Xinhui Zhu, Chao Zeng, Qifan Wang, Qiang Zhou, Qinghua Tao, Minhao Liu, Jianlin Lei, Chuangye Yan, Yigong Shi
Software Mentions: 2
Published: over 6 years ago
10.3390/cells8060570
An Emerin LEM-Domain Mutation Impairs Cell Response to Mechanical Stress
Cited by: 12
Author(s): Nada Essawy, Camille Samson, Ambre Petitalot, Sophie Moog, Anne Bigot, Isaline Herrada, Agathe Marcelot, Ana-Andreea Arteni, Catherine Coirault, Sophie Zinn‐Justin
Software Mentions: 2
Published: over 7 years ago
10.1002/cctc.202100110
A Structural View on the Stereospecificity of Plant Borneol‐Type Dehydrogenases
Cited by: 10
Author(s): Andrea M Chánique, Nicole Dimos, Ivana Drienovská, Elia Calderini, Mónica P. Pantín, Carl P. O. Helmer, Michaël Hofer, Volker Sieber, Loreto P. Parra, Bernhard Loll, Robert Kourist
Software Mentions: 2
Published: over 5 years ago
10.1002/cbic.201800462
Structure and Catalytic Mechanism of a Bacterial Friedel–Crafts Acylase
Cited by: 23
Author(s): Tea Pavkov‐Keller, Nina G. Schmidt, Anna Żądło‐Dobrowolska, Wolfgang Kroutil, Karl Gruber
Software Mentions: 2
Published: almost 8 years ago
10.1002/cbic.201300136
The Structure of Glycerol Trinitrate Reductase NerA from<i>Agrobacterium radiobacter</i>Reveals the Molecular Reason for Nitro‐ and Ene‐Reductase Activity in OYE Homologues
Cited by: 10
Author(s): Gustav Oberdorfer, Alexandra Binter, Silvia Wallner, Katharina Durchschein, Mélanie Hall, Kurt Faber, Peter Macheroux, Karl Gruber
Software Mentions: 2
Published: over 13 years ago
10.1038/s42003-020-01546-4
Structural basis of Naa20 activity towards a canonical NatB substrate
Cited by: 3
Author(s): Dominik Layer, Jürgen Kopp, Miriam Fontanillo, Maja Köhn, Karine Lapouge, Irmgard Sinning
Software Mentions: 2
Published: almost 6 years ago
10.1038/s42003-019-0562-8
Identification of an amphipathic peptide sensor of the Bacillus subtilis fluid membrane microdomains
Cited by: 5
Author(s): Yiping Jiang, Xin Dai, Mingming Qin, Zhihong Guo
Software Mentions: 2
Published: about 7 years ago
10.1038/s42003-020-01266-9
Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy
Cited by: 17
Author(s): Hyunjin Cho, Yuri Choi, Kyoung‐Wook Min, Jung Bae Son, Hyojin Park, Hyung Ho Lee, Seokhee Kim
Software Mentions: 2
Published: about 6 years ago
10.1038/s42003-021-01739-5
Structure–function studies of ultrahigh molecular weight isoprenes provide key insights into their biosynthesis
Cited by: 2
Author(s): Hiroyuki Kajiura, Takumi Yoshizawa, Yuji Tokumoto, Nobuaki Suzuki, Shinya Takeno, Kanokwan Jumtee Takeno, Takuya Yamashita, Shun‐ichi Tanaka, Yoshinobu Kaneko, Kazuhito Fujiyama, Hideki Matsumura, Yasuhiro Nakazawa
Software Mentions: 2
Published: over 5 years ago
10.1038/s42003-019-0426-2
15-deoxy-Δ12,14-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism
Cited by: 14
Author(s): Giancarlo Abis, Rebecca L. Charles, J. Kopec, Wyatt W. Yue, R. Andrew Atkinson, Tam T. Bui, Steven Lynham, Popova Sn, Yin-Biao Sun, Franca Fraternali, Philip Eaton, Maria R. Conte
Software Mentions: 2
Published: over 7 years ago
10.1038/s42003-018-0236-y
The crystal structure of a tetrahydrofolate-bound dihydrofolate reductase reveals the origin of slow product release
Cited by: 19
Author(s): Heidi B. Cao, Mu Gao, Hongyi Zhou, Jeffrey Skolnick
Software Mentions: 2
Published: almost 8 years ago
10.1038/s42003-021-01750-w
The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2
Cited by: 43
Author(s): Sensen Zhang, Jun Zhou, Yuebin Zhang, Tianya Liu, Perrine Friedel, Wei Zhuo, Suma Somasekharan, Kasturi Roy, Laixing Zhang, Yang Liu, Xianbin Meng, Haiteng Deng, Wenwen Zeng, Guohui Li, Bliss Forbush, Maojun Yang
Software Mentions: 2
Published: over 5 years ago
10.1038/s42003-021-02473-8
The structure of an archaeal oligosaccharyltransferase provides insight into the strict exclusion of proline from the N-glycosylation sequon
Cited by: 4
Author(s): Yuya Taguchi, Tomohiro Yamasaki, Marie Ishikawa, Yuki Kawasaki, Ryuji Yukimura, Maki Mitani, Kunio Hirata, Daisuke Kohda
Software Mentions: 2
Published: about 5 years ago
10.1038/s42003-021-02068-3
Identification of a peptide motif that potently inhibits two functionally distinct subunits of Shiga toxin
Cited by: 5
Author(s): Miho Watanabe-Takahashi, Masakazu Tamada, Masuo Senda, M. Hibino, Eihan Shimizu, Akiko Okuta, Atsuo Miyazawa, Toshiya Senda, Kiyotaka Nishikawa
Software Mentions: 2
Published: over 5 years ago
10.1038/s42003-020-01147-1
Molecular basis of the lipid-induced MucA-MucB dissociation in Pseudomonas aeruginosa
Cited by: 6
Author(s): Tao Li, Libang He, Changcheng Li, Mei Kang, Yingjie Song, Yuanfeng Zhu, Yanjiao Shen, Ninglin Zhao, Chang Zhao, Jing Yang, Qin Huang, Xingyu Mou, Aiping Tong, Jinliang Yang, Zhenling Wang, Chengjie Ji, Hong Li, Hong Tang, Rui Bao
Software Mentions: 2
Published: about 6 years ago
10.1038/s42003-021-02326-4
Structure-based insights into evolution of rhodopsins
Cited by: 13
Author(s): Dmitrii Zabelskii, Natalia I. Dmitrieva, Oleksandr Volkov, Vitaly Shevchenko, Kirill Kovalev, Taras Balandin, Dmytro Soloviov, Roman Astashkin, Egor V. Zinovev, Alexey Alekseev, Ekaterina Round, Vitaly Polovinkin, Igor Chizhov, Andrey Rogachev, Ivan Okhrimenko, Valentin Borshchevskiy, Vladimir Chupin, Georg Büldt, Natalia Yutin, Ernst Bamberg, Eugene V. Koonin, Valentin Gordeliy
Software Mentions: 2
Published: over 5 years ago
10.1038/s42003-020-01633-6
Elucidating the tunability of binding behavior for the MERS-CoV macro domain with NAD metabolites
Cited by: 3
Author(s): Meng-Hsuan Lin, Chao-Cheng Cho, Yi‐Chih Chiu, Chia‐Yu Chien, Yiping Huang, Chi‐Fon Chang, Chun‐Hua Hsu
Software Mentions: 2
Published: over 5 years ago
10.1038/s42003-020-01412-3
Structural basis of superinfection exclusion by bacteriophage T4 Spackle
Cited by: 14
Author(s): Ke Shi, Justin Oakland, Fredy Kurniawan, Nicholas H. Moeller, Surajit Banerjee, Hideki Aihara
Software Mentions: 2
Published: almost 6 years ago
10.1038/s42003-020-01208-5
Diversity in the intrinsic apoptosis pathway of nematodes
Cited by: 3
Author(s): Neil D. Young, Tiffany J Harris, Marco Evangelista, Sharon Tran, Merridee A. Wouters, Tatiana P. Soares da Costa, Nadia J. Kershaw, Robin B. Gasser, Brian J. Smith, Erinna F. Lee, W. Douglas Fairlie
Software Mentions: 2
Published: about 6 years ago
10.1038/s42003-020-01640-7
Molecular basis of IRGB10 oligomerization and membrane association for pathogen membrane disruption
Cited by: 8
Author(s): Hyekyung Ha, Hye Lin Chun, So Yeon Lee, Jin Ho Jeong, Yeon-Gil Kim, Hyun Ho Park
Software Mentions: 2
Published: almost 6 years ago
10.1038/s42003-020-01223-6
Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate
Cited by: 10
Author(s): Maren Kirstin Schuhmacher, Serap Beldar, Mina S Khella, Alexander Bröhm, Jan Ludwig, W. Tempel, Sara Weirich, Jinrong Min, Albert Jeltsch
Software Mentions: 2
Published: about 6 years ago
10.1038/s42003-020-0941-1
Characterization of a toxin-antitoxin system in Mycobacterium tuberculosis suggests neutralization by phosphorylation as the antitoxicity mechanism
Cited by: 26
Author(s): Xia Yu, Xiaopan Gao, Keqing Zhu, Han Yin, Xu-Jian Mao, Justyna Aleksandra Wojdyla, Bo Qin, Hairong Huang, Meitian Wang, Yicheng Sun, Sheng Cui
Software Mentions: 2
Published: over 6 years ago
10.1038/s42003-020-01531-x
Structural insights into photoactivation of plant Cryptochrome-2
Cited by: 27
Author(s): Malathy Palayam, Jagadeesan Ganapathy, Angelica M. Guercio, Lior Tal, Samuel L. Deck, Nitzan Shabek
Software Mentions: 2
Published: almost 6 years ago
10.1038/s42003-020-01283-8
Structural role of essential light chains in the apicomplexan glideosome
Cited by: 8
Author(s): Samuel Pažický, Karthikeyan Dhamotharan, Karol Kaszuba, Haydyn D. T. Mertens, Tim‐Wolf Gilberger, Dmitri I. Svergun, Jan Kosiński, Ulrich Weininger, Christian Löw
Software Mentions: 2
Published: about 6 years ago
10.1038/s42003-018-0123-6
In situ serial crystallography for rapid de novo membrane protein structure determination
Cited by: 26
Author(s): Chia-Ying Huang, V. Oliéric, Nicole Howe, Rangana Warshamanage, T. Weinert, Ezequiel Panepucci, Lutz Vogeley, Shibom Basu, Kay Diederichs, Martin Caffrey, Meitian Wang
Software Mentions: 2
Published: about 8 years ago
10.1016/j.csbj.2021.06.006
A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis
Cited by: 13
Author(s): P. Gupta, S.E. Thomas, Shaymaa A. Zaidan, Maria A. Pasillas, J. Cory-Wright, Víctor Sebastián-Pérez, Ailidh Burgess, Emma Cattermole, C. Meghir, Chris Abell, Anthony G. Coyne, William R. Jacobs, Tom L. Blundell, Sangeeta Tiwari, V. Mendes
Software Mentions: 2
Published: almost 6 years ago
10.1016/j.csbj.2015.08.005
Integrative Modeling of Macromolecular Assemblies from Low to Near-Atomic Resolution
Cited by: 22
Author(s): Xiaojun Xu, Yan Cheng, Robert M. Wohlhueter, Ivaylo Ivanov
Software Mentions: 2
Published: almost 12 years ago
10.1016/j.csbj.2021.05.035
Altered APE1 activity on abasic ribonucleotides is mediated by changes in the nucleoside sugar pucker
Cited by: 6
Author(s): N.M. Hoitsma, Timothy H. Click, Pratul K. Agarwal, Bret Freudenthal
Software Mentions: 2
Published: almost 6 years ago
10.1021/acs.cgd.0c01608
Production of Cross-Linked Lipase Crystals at a Preparative Scale
Cited by: 10
Author(s): Raquel Fernández-Penas, Cristóbal Verdugo‐Escamilla, Sergio Martínez‐Rodríguez, José A. Gavira
Software Mentions: 2
Published: over 5 years ago
10.1016/j.dib.2017.10.051
Datasets, processing and refinement details for Mtb -AnPRT: inhibitor structures with various space groups
Cited by: 2
Author(s): G.L. Evans, Daniel P. Furkert, Nacim Abermil, Preeti Kundu, Katrina M. de Lange, E.J. Parker, Margaret A. Brimble, Edward N. Baker, J.S. Lott
Software Mentions: 2
Published: almost 9 years ago
10.1080/10717544.2018.1428245
HSA-based multi-target combination therapy: regulating drugs’ release from HSA and overcoming single drug resistance in a breast cancer model
Cited by: 31
Author(s): Yanzi Gou, Zhenlei Zhang, Dongyang Li, Lei Zhao, Meiling Cai, Zhigang Sun, Yongping Li, Yao Zhang, Hina Khan, Hongbing Sun, Tao Wang, Hong Liang, Feng Yang
Software Mentions: 2
Published: almost 9 years ago
10.15252/embj.2020105908
Structure and elevator mechanism of the mammalian sodium/proton exchanger NHE9
Cited by: 27
Author(s): Iven Winkelmann, Ryota Matsuoka, Pascal Meier, Denis Shutin, Chen‐Ou Zhang, Laura Orellana, Ricky Sexton, Michael Landreh, Carol V. Robinson, Oliver Beckstein, David Drew
Software Mentions: 2
Published: almost 6 years ago
10.15252/embj.2018101414
Coupling of ATPase activity, microtubule binding, and mechanics in the dynein motor domain
Cited by: 19
Author(s): Stefan Niekamp, Nicolas Coudray, Nan Zhang, Ronald D. Vale, Gira Bhabha
Software Mentions: 2
Published: over 7 years ago
10.15252/embj.2020106164
Cryo‐EM reveals the complex architecture of dynactin's shoulder region and pointed end
Cited by: 15
Author(s): C.K. Lau, Francis J. O’Reilly, S. Balaji, Samuel E Lacey, Juri Rappsilber, Andrew P. Carter
Software Mentions: 2
Published: over 5 years ago
10.15252/embj.2019103234
Structural basis for centromere maintenance by <i>Drosophila</i> <scp>CENP</scp> ‐A chaperone <scp>CAL</scp> 1
Cited by: 27
Author(s): Bethan Medina‐Pritchard, Vasiliki Lazou, Juan Zou, Olwyn Byron, Maria Alba Abad, Juri Rappsilber, Patrick Heun, A. Arockia Jeyaprakash
Software Mentions: 2
Published: over 6 years ago
10.15252/embr.202052325
NeutrobodyPlex—monitoring SARS‐CoV‐2 neutralizing immune responses using nanobodies
Cited by: 35
Author(s): Teresa R. Wagner, E. Ostertag, Philipp Kaiser, Marius Gramlich, Natalia Ruétalo, Daniel Junker, Julia Haering, Bjoern Traenkle, Matthias Becker, Alex Dulovic, H Schweizer, Stefan Nueske, Armin M. Scholz, Anne Zeck, Katja Schenke‐Layland, Annika Nelde, Monika Strengert, Juliane S. Walz, Georg Zocher, Thilo Stehle, Michael Schindler, Nicole Schneiderhan‐Marra, Ulrich Rothbauer
Software Mentions: 2
Published: over 5 years ago
10.15252/embr.201745680
Active site alanine mutations convert deubiquitinases into high‐affinity ubiquitin‐binding proteins
Cited by: 40
Author(s): Marie E. Morrow, Michael T. Morgan, Marcello Clerici, Kateřina Growková, Ming Yan, David Komander, Titia K. Sixma, Michal Šimíček, Cynthia Wolberger
Software Mentions: 2
Published: about 8 years ago
10.15252/embr.201847183
Structural basis of <scp>HEAT</scp> ‐kleisin interactions in the human condensin I subcomplex
Cited by: 18
Author(s): Kodai Hara, Kazuhisa Kinoshita, Tomoko Migita, Kei Murakami, Kenichiro Shimizu, K. Takeuchi, Takeshi Hirano, Hiroshi Hashimoto
Software Mentions: 2
Published: over 7 years ago
10.1080/22221751.2020.1865840
Structure of the multiple functional domains from coronavirus nonstructural protein 3
Cited by: 8
Author(s): Mengxia Li, Gang Ye, Yu Si, Zhou Shen, Zhu Liu, Yuejun Shi, Shaobo Xiao, Zhen F. Fu, Guiqing Peng
Software Mentions: 2
Published: almost 6 years ago
10.1080/22221751.2019.1707716
Structural characterization of glycinamide-RNase-transformylase T from <i>Mycobacterium tuberculosis</i>
Cited by: 1
Author(s): Chuanbo Cong, Zuliang Liu, Liguo Liu, Jianmin Wang, Qi Jin
Software Mentions: 2
Published: almost 7 years ago
10.1080/22221751.2021.1899770
The preclinical inhibitor GS441524 in combination with GC376 efficaciously inhibited the proliferation of SARS-CoV-2 in the mouse respiratory tract
Cited by: 33
Author(s): Yuejun Shi, Lei Shuai, Zhiyuan Wen, Chong Wang, Yuanyuan Yan, Zhe Jiao, Fenglin Guo, Zhen F. Fu, Huanchun Chen, Zhigao Bu, Guiqing Peng
Software Mentions: 2
Published: almost 6 years ago
10.1289/ehp.1306902
Mimicking of Estradiol Binding by Flame Retardants and Their Metabolites: A Crystallographic Analysis
Cited by: 79
Author(s): R.A. Gosavi, Gabriel A. Knudsen, Linda S. Birnbaum, Lars C. Pedersen
Software Mentions: 2
Published: about 13 years ago
10.1016/j.ejmech.2018.04.035
Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines
Cited by: 52
Author(s): Matthias G. J. Baud, Matthias R. Bauer, Lorena Verduci, Felix A. Dingler, Ketan Patel, Debmalya Roy, A.C. Joerger, Alan R. Fersht
Software Mentions: 2
Published: over 8 years ago
10.1074/jbc.M116.743948
The Mechanism by Which Arabinoxylanases Can Recognize Highly Decorated Xylans
Cited by: 34
Author(s): Aurore Labourel, Lucy I. Crouch, Joana L. A. Brás, Adam Jackson, Artur Rogowski, Joe Gray, Madhav P. Yadav, Bernard Henrissat, Carlos M. G. A. Fontes, Harry J. Gilbert, Shabir Najmudin, Arnaud Baslé, Fiona Cuskin
Software Mentions: 2
Published: about 10 years ago
10.1074/jbc.M116.748160
Ligand-bound Structures and Site-directed Mutagenesis Identify the Acceptor and Secondary Binding Sites of Streptomyces coelicolor Maltosyltransferase GlgE
Cited by: 11
Author(s): Karl Syson, Clare E. M. Stevenson, Farzana Miah, J. Elaine Barclay, Minhong Tang, Andrii Gorelik, Abdur Rashid, David M. Lawson, Stephen Bornemann
Software Mentions: 2
Published: about 10 years ago
10.1074/jbc.M116.749713
Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
Cited by: 27
Author(s): Shaimaa Waz, Teruya Nakamura, Keisuke Hirata, Yukari Koga‐Ogawa, Mami Chirifu, Takao Arimori, Taro Tamada, Shinji Ikemizu, Yusaku Nakabeppu, Yuriko Yamagata
Software Mentions: 2
Published: over 9 years ago
10.1074/jbc.M117.781948
Structure of the WipA protein reveals a novel tyrosine protein phosphatase effector from Legionella pneumophila
Cited by: 10
Author(s): Nikos Pinotsis, Gabriel Waksman
Software Mentions: 2
Published: over 9 years ago
10.1074/jbc.M117.780395
The crystal structure of mammalian inositol 1,3,4,5,6-pentakisphosphate 2-kinase reveals a new zinc-binding site and key features for protein function
Cited by: 7
Author(s): Elsa Franco-Echevarría, Julia Sanz‐Aparicio, Charles A. Brearley, Juana María González-Rubio, Beatriz González
Software Mentions: 2
Published: over 9 years ago
10.1074/jbc.M117.797811
Discovery of a microbial transglutaminase enabling highly site-specific labeling of proteins
Cited by: 42
Author(s): Wojtek Steffen, Fu Chong Ko, Jigar Patel, Victor I. Lyamichev, Thomas Albert, Jörg Benz, M.G. Rudolph, Frank Bergmann, Thomas Streidl, Peter Kratzsch, Mara Boenitz-Dulat, Tobias Oelschlaegel, Michael Schraeml
Software Mentions: 2
Published: about 9 years ago
10.1074/jbc.M117.802587
Phosphorylation of human enhancer filamentation 1 (HEF1) stimulates interaction with Polo-like kinase 1 leading to HEF1 localization to focal adhesions
Cited by: 6
Author(s): Kyung Ho Lee, Jeong Ah Hwang, Sun Ok Kim, Jung Hee Kim, Sang Chul Shin, Eunice Eun Kyeong Kim, Kyung S. Lee, Kunsoo Rhee, Byeong Hwa Jeon, Jeong Kyu Bang, Hyunjoo Cha-Molstad, Nak-Kyun Soung, Jae Hyuk Jang, Sung-Kyun Ko, Hee Gu Lee, Jong Seog Ahn, Yongtae Kwon, Bo Yeon Kim
Software Mentions: 2
Published: almost 9 years ago
10.1074/jbc.M117.809657
Prodomain–growth factor swapping in the structure of pro-TGF-β1
Cited by: 29
Author(s): Bo Zhao, Shutong Xu, Xiao Dong, Chafen Lu, Timothy A. Springer
Software Mentions: 2
Published: over 8 years ago
10.1074/jbc.RA117.000119
Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects
Cited by: 45
Author(s): Wei Chen, Mingli Qu, Yong Zhou, Qing Yang
Software Mentions: 2
Published: over 8 years ago
10.1074/jbc.M117.816348
Exceptionally high-affinity Ras binders that remodel its effector domain
Cited by: 33
Author(s): John H. McGee, So Youn Shim, Seung-Joo Lee, Paige Swanson, Sam Y. Jiang, Michael A. Durney, Gregory L. Verdine
Software Mentions: 2
Published: over 8 years ago
10.1074/jbc.RA118.005405
InhA, the enoyl-thioester reductase from Mycobacterium tuberculosis forms a covalent adduct during catalysis
Cited by: 15
Author(s): Bastian Vögeli, Raoul Rosenthal, Gabriele Stoffel, T. Wagner, Patrick Kiefer, Niña Socorro Cortina, Seigo Shima, Tobias J. Erb
Software Mentions: 2
Published: almost 8 years ago
10.1074/jbc.RA118.004227
Oxidative cyclization of N-methyl-dopa by a fungal flavoenzyme of the amine oxidase family
Cited by: 3
Author(s): Majd Lahham, Tea Pavkov‐Keller, Michael Fuchs, Johannes Niederhauser, Gabriel Chalhoub, Bastian Daniel, Wolfgang Kroutil, Karl Gruber, Peter Macheroux
Software Mentions: 2
Published: almost 8 years ago
10.1074/jbc.RA118.003857
The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel
Cited by: 33
Author(s): Stephanie J. Ward, Hayley E. Gratton, Peni Indrayudha, Camille Michavila, Rishov Mukhopadhyay, Sigrun K. Maurer, Simon G. Caulton, Jonas Emsley, Ingrid Dreveny
Software Mentions: 2
Published: almost 8 years ago